{"id":"W4206360524","doi":"10.1186/s13287-021-02681-3","title":"Human MuStem cells repress T-cell proliferation and cytotoxicity through both paracrine and contact-dependent pathways","year":2022,"lang":"en","type":"article","venue":"Stem Cell Research & Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Université de Montpellier; Centre National de la Recherche Scientifique; European Regional Development Fund; Institute of Genetics; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Cytotoxic T cell; Immune system; Mesenchymal stem cell; Biology; Paracrine signalling; Cell biology; Stem cell; Inflammation; Bone marrow; T cell; Immunology; Cancer research; In vitro; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001267335,0.0002616142,0.0002149482,0.0001312431,0.00008496217,0.0002273906,0.0001162981,0.0002011008,0.002453699],"category_scores_gemma":[0.0001380219,0.00004951171,0.0002212524,0.00008362473,0.0001430964,0.0001179869,0.0001762087,0.0003714389,0.000466919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009262424,"about_ca_system_score_gemma":0.00008936322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000136409,"about_ca_topic_score_gemma":0.0002311624,"domain_scores_codex":[0.999867,0.00003789012,0.00001138714,0.00002053113,0.00003321851,0.0000298833],"domain_scores_gemma":[0.9998863,0.00004665733,0.00002048717,0.00002030292,0.000009982467,0.00001622838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000267708,0.00005388629,0.0002947589,0.00003755997,0.000004171782,0.00005458974,0.00001836863,0.00004583356,0.9973122,0.00005637914,0.0000556891,0.001798945],"study_design_scores_gemma":[0.00003557454,0.0008871425,0.003957549,0.000007960268,0.00001729666,0.0003797291,0.00003439215,0.0004907688,0.9901337,0.00003321527,0.004020347,0.000002285872],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944338,0.002012313,0.001628688,0.00006930993,0.00003080994,0.00002513516,0.0002275352,0.00004889532,0.001523591],"genre_scores_gemma":[0.9938045,0.0007407507,0.001548526,0.00007530658,0.00004220893,0.00003517223,0.0006629836,0.00001145979,0.003079128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002453699,"threshold_uncertainty_score":0.008208394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05072896897943589,"score_gpt":0.3177107413597899,"score_spread":0.266981772380354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}