{"id":"W4206361796","doi":"10.3410/f.13327968.14743056","title":"Faculty Opinions recommendation of Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.","year":2011,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Longevity; Biology; Drosophila melanogaster; Caenorhabditis elegans; Sirtuin; Genetics; Transgene; Drosophila (subgenus); Allele; Ageing; Model organism; Gene; Acetylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002756979,0.0005704272,0.0004932981,0.001621189,0.001411159,0.002458883,0.001075733,0.001951415,0.2719011],"category_scores_gemma":[0.007303721,0.0004092814,0.000432057,0.001890678,0.0005791558,0.001195631,0.00124082,0.001612122,0.1399013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0020369,"about_ca_system_score_gemma":0.005983145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01243363,"about_ca_topic_score_gemma":0.02991185,"domain_scores_codex":[0.9975566,0.0001750222,0.0001677828,0.0002601784,0.001638897,0.0002015185],"domain_scores_gemma":[0.9897242,0.000526142,0.0007357021,0.0009300784,0.006548249,0.001535647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002632492,0.000171697,0.001952497,0.000816124,0.00003297528,0.0002168914,0.0001398015,0.0001803644,0.05736442,0.002721435,0.7315999,0.2045406],"study_design_scores_gemma":[0.00002406886,0.0000630804,0.004747634,0.0001749665,0.000014216,0.00007455903,0.00008036943,0.0001502146,0.006563814,0.0004285697,0.9876602,0.00001826684],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"dataset","genre_scores_codex":[0.01208213,0.003691645,0.008490343,0.04926024,0.02890462,0.0007421249,0.03310207,0.004586119,0.8591408],"genre_scores_gemma":[0.04017464,0.007599695,0.009554059,0.01201484,0.002985322,0.0004504992,0.02276492,0.001400629,0.9030553],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.2719011,"threshold_uncertainty_score":0.9095999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01805976217980107,"score_gpt":0.3095954381418157,"score_spread":0.2915356759620147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}