{"id":"W4206362690","doi":"10.1016/j.biopsych.2021.11.015","title":"Chicken or Egg? Untangling the Associations Between Personality Traits and Alzheimer’s Disease Pathology","year":2022,"lang":"en","type":"letter","venue":"Biological Psychiatry","topic":"Personality Disorders and Psychopathology","field":"Psychology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Alzheimer Society","keywords":"Neuropathology; Neuroticism; Conscientiousness; Big Five personality traits; Personality; Psychology; Disease; Clinical psychology; Personality pathology; Alzheimer's disease; Developmental psychology; Medicine; Pathology; Personality disorders; Extraversion and introversion; Psychoanalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.001270088,0.0007406144,0.001044636,0.0001435294,0.001026819,0.00007552832,0.001059832,0.001800758,0.008749505],"category_scores_gemma":[0.0001964798,0.0004678463,0.0005544125,0.000385211,0.0008686284,0.00004542679,0.0002902013,0.004222596,0.000142283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006554071,"about_ca_system_score_gemma":0.0002252358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001704416,"about_ca_topic_score_gemma":0.00009675905,"domain_scores_codex":[0.9927974,0.003184457,0.0008361349,0.00165674,0.0004129083,0.0011123],"domain_scores_gemma":[0.997098,0.001353998,0.0005928247,0.0006677022,0.00005538294,0.0002320608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0002895718,0.0002151416,0.2111695,0.00002269425,0.0005122024,0.0003597692,0.0008219306,1.716908e-7,5.104463e-7,0.001805891,0.7825427,0.002259886],"study_design_scores_gemma":[0.000537521,0.0003205052,0.5261108,0.000009357221,0.0003785953,0.00006243847,0.0004430871,4.74997e-7,6.077769e-9,0.005969888,0.4657067,0.000460671],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1027665,0.01972964,0.00003494749,0.8562717,0.004391177,0.001130473,0.009130997,0.0002689212,0.006275661],"genre_scores_gemma":[0.05644144,0.0003484589,0.0002347198,0.9226714,0.01289833,0.0006609731,0.004460049,0.0001279733,0.002156615],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.316836,"threshold_uncertainty_score":0.9997773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1025935863261041,"score_gpt":0.3480551118126722,"score_spread":0.2454615254865681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}