{"id":"W4206411001","doi":"10.3389/fphys.2021.763933","title":"Influence of High Hemoglobin-Oxygen Affinity on Humans During Hypoxia","year":2022,"lang":"en","type":"review","venue":"Frontiers in Physiology","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University; University of Waterloo","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Mayo Foundation for Medical Education and Research; Mayo Clinic","keywords":"Hypoxia (environmental); Hemoglobin; Oxygen; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001406575,0.0004274744,0.001464007,0.000233692,0.00009766974,0.000005123627,0.0007556314,0.0004753737,0.00006188695],"category_scores_gemma":[0.00008369955,0.0004126853,0.0003619654,0.0002354706,0.0001768142,0.000003680125,0.0004230476,0.0005086251,0.0000153233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009088022,"about_ca_system_score_gemma":0.0002149357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004439133,"about_ca_topic_score_gemma":0.00001268224,"domain_scores_codex":[0.9977201,0.0003416682,0.0005956789,0.0007652319,0.0001473254,0.0004300373],"domain_scores_gemma":[0.9986935,0.00002889014,0.000367065,0.0008266059,0.00002717135,0.00005677677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00375887,0.005985008,0.002013289,0.09756974,0.009090379,0.0005433489,0.000803892,0.02097929,0.1792828,0.002739039,0.1254062,0.5518282],"study_design_scores_gemma":[0.0004577001,0.0003817581,0.003695292,0.0004577047,0.000117894,0.000008432978,0.00001345638,3.735125e-7,0.0006631665,0.0001920207,0.9935374,0.0004747618],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2705446,0.7280605,0.000004332381,0.000004205276,0.0005407093,0.0004095487,0.0001426768,0.00001227284,0.000281214],"genre_scores_gemma":[0.01707776,0.9812003,0.0002846425,0.0000881458,0.0002261727,0.0001665477,0.0006419822,0.00005808198,0.0002563224],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8681313,"threshold_uncertainty_score":0.9998325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01489186928918932,"score_gpt":0.2625418066204325,"score_spread":0.2476499373312432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}