{"id":"W4206446840","doi":"10.1016/j.tcm.2022.01.002","title":"MEF2 in cardiac hypertrophy in response to hypertension","year":2022,"lang":"en","type":"review","venue":"Trends in Cardiovascular Medicine","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Mef2; Heart failure; Muscle hypertrophy; Pressure overload; Pathological; Cardiology; Medicine; Cardiac hypertrophy; Internal medicine; Cardiac myocyte; Risk factor; Left ventricular hypertrophy; Blood pressure; Enhancer; Transcription factor; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007697689,0.0009321795,0.0105838,0.006132053,0.00005903484,0.00001195353,0.0003455014,0.0006003016,0.0002579742],"category_scores_gemma":[0.0008999481,0.0007095917,0.004421136,0.005646581,0.0001100392,0.00005592857,0.0003659166,0.002016502,0.00003361495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001811622,"about_ca_system_score_gemma":0.0003848351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001101515,"about_ca_topic_score_gemma":0.00003791973,"domain_scores_codex":[0.9915559,0.002277066,0.001862415,0.001569533,0.001829047,0.0009060749],"domain_scores_gemma":[0.9965371,0.0006265175,0.0001506183,0.002247969,0.0000609979,0.0003767791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004401797,0.000113215,0.0001035927,0.002748473,0.000857949,0.002246346,0.0003479403,0.0004320079,0.0000328295,0.000002915387,0.0009596017,0.991715],"study_design_scores_gemma":[0.003278366,0.0004081886,0.003371142,0.02194404,0.002939666,0.0005399685,0.0002069313,0.00003924592,6.206939e-7,0.0000023778,0.9666489,0.0006206038],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001021426,0.9930668,0.000005843132,0.0004638636,0.001534297,0.001343262,0.00003094261,0.00006305053,0.002470547],"genre_scores_gemma":[0.001353728,0.995792,0.0002130933,0.0002467816,0.0008541385,0.0004880686,0.0003746919,0.0002210601,0.000456482],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9910944,"threshold_uncertainty_score":0.9995355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08455360872052908,"score_gpt":0.3406385051905677,"score_spread":0.2560848964700386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}