{"id":"W4206474394","doi":"10.3390/cimb44010023","title":"Multi-Omics Integration and Network Analysis Reveal Potential Hub Genes and Genetic Mechanisms Regulating Bovine Mastitis","year":2022,"lang":"en","type":"review","venue":"Current Issues in Molecular Biology","topic":"Milk Quality and Mastitis in Dairy Cows","field":"Agricultural and Biological Sciences","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Mastitis; Biology; Gene; Genetics; Computational biology; Transcriptome; Gene regulatory network; Candidate gene; In silico; Genome-wide association study; Microarray analysis techniques; Single-nucleotide polymorphism; Gene expression; Genotype; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004328972,0.0003841246,0.001196637,0.00009231425,0.0002034297,0.00006314507,0.0003130889,0.0003179662,0.0002197261],"category_scores_gemma":[0.0001071318,0.0001974919,0.0002691465,0.0006869565,0.0001385298,0.00003155559,0.0005659384,0.0003983899,0.000001924781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004400716,"about_ca_system_score_gemma":0.0000147133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001608251,"about_ca_topic_score_gemma":0.0004644079,"domain_scores_codex":[0.9970425,0.0009928335,0.0006735877,0.000790351,0.0001255915,0.0003750997],"domain_scores_gemma":[0.9992744,0.0001490001,0.000328904,0.0001354358,0.00002705985,0.0000851486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005071151,0.00003210045,0.0000668162,0.0003857815,0.0001061259,0.00002040565,0.00002454272,0.00003679723,0.000647402,0.0009249925,0.00002156814,0.9977284],"study_design_scores_gemma":[0.0002231835,0.0004236817,0.0004314366,0.001081175,0.001562173,0.00009307143,0.00007884009,0.001536402,0.0000188044,0.004346952,0.9892952,0.0009090542],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002809328,0.9874563,0.008430136,0.00004785849,0.0005449683,0.000488598,0.0001852535,0.00003083452,0.000006742365],"genre_scores_gemma":[0.0004604627,0.9871338,0.009615476,0.00003155857,0.0002675219,0.0000967355,0.002351083,0.000004311281,0.00003907521],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9968193,"threshold_uncertainty_score":0.8053487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04647803854482219,"score_gpt":0.3314755659236511,"score_spread":0.2849975273788289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}