{"id":"W4206476135","doi":"10.3390/microorganisms10020223","title":"Modulation of Streptococcus mutans Adherence to Hydroxyapatite by Engineered Salivary Peptides","year":2022,"lang":"en","type":"article","venue":"Microorganisms","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Fundação de Amparo à Pesquisa do Estado de São Paulo; Canada Foundation for Innovation; International Association for Dental Research","keywords":"Streptococcus mutans; Saliva; Microbiology; Biofilm; Proteome; Bacteria; Streptococcus gordonii; Streptococcus sanguinis; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002028998,0.000147973,0.0002289456,0.0001160039,0.000203013,0.00002725822,0.0004036218,0.00007930334,0.007869264],"category_scores_gemma":[0.00004733729,0.0001657182,0.00006438245,0.0004636218,0.00006063196,0.00007946745,0.0002994177,0.0002639048,0.0004173926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009037834,"about_ca_system_score_gemma":0.00005967061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004289606,"about_ca_topic_score_gemma":0.00009845432,"domain_scores_codex":[0.9987293,0.0001479411,0.0003089905,0.0003270705,0.0001889476,0.0002977522],"domain_scores_gemma":[0.9993759,0.00004865883,0.00007921595,0.0003314567,0.00008314521,0.00008159242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003897754,0.00008628405,0.01414054,0.00002144657,0.00002966152,0.00001976992,0.0004277419,0.0002851577,0.9642295,0.00005059372,0.01958844,0.001081864],"study_design_scores_gemma":[0.0005708193,0.0005959239,0.0379834,0.0000160939,0.00001212255,0.00005732434,0.0002900661,0.0001032724,0.9438596,0.0001090534,0.01611316,0.0002891068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964842,0.0001992456,0.0007825476,0.00007783721,0.0003123001,0.0003910155,0.001374366,0.0000642235,0.0003142479],"genre_scores_gemma":[0.9943246,0.00000414535,0.000598616,0.0001076394,0.0000344604,0.00005722799,0.0003694956,0.00003108228,0.004472779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02384286,"threshold_uncertainty_score":0.9930377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141617806189895,"score_gpt":0.2682515779769823,"score_spread":0.2540897973579928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}