{"id":"W4206476852","doi":"10.3390/molecules27020491","title":"In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties","year":2022,"lang":"en","type":"article","venue":"Molecules","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Willow Biosciences (Canada)","funders":"","keywords":"Cannabidiol; Pharmacology; Human skin; Cannabinoid; Tumor necrosis factor alpha; Cytokine; Biochemistry; Chemistry; Biology; Immunology; Medicine; Cannabis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002565467,0.0001574004,0.0005442049,0.000280566,0.0001004305,0.00001078256,0.00008133137,0.00004908093,0.00002141572],"category_scores_gemma":[0.0003445058,0.0001266711,0.00005740582,0.0002998816,0.0003091261,0.00005798197,0.000129808,0.0002761841,2.277708e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001328092,"about_ca_system_score_gemma":0.00106605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002302999,"about_ca_topic_score_gemma":0.0003200852,"domain_scores_codex":[0.9972835,0.0005639125,0.0006002061,0.0004011491,0.0008538998,0.0002972905],"domain_scores_gemma":[0.9990076,0.00001154281,0.0002489044,0.0002727047,0.0003189812,0.0001402065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004761653,0.0009646033,0.07326043,0.002533862,0.0002190039,0.00007156188,0.005032298,0.00009239143,0.7664602,0.00001613862,0.001522335,0.1450655],"study_design_scores_gemma":[0.008526647,0.002749699,0.5916196,0.0006055781,0.0002681938,0.0002652354,0.003764619,0.01014063,0.380576,0.00002440223,0.001050672,0.0004088402],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986964,0.003681096,0.000006221566,0.007815128,0.00003269795,0.001421567,0.0000276933,0.00001231051,0.00003932104],"genre_scores_gemma":[0.9991821,0.00006658029,0.00009901509,0.0001791863,0.00003819173,0.0002540212,0.000006185238,0.00002946078,0.0001452512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5183591,"threshold_uncertainty_score":0.5165498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03125654880542058,"score_gpt":0.3139057169783703,"score_spread":0.2826491681729497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}