{"id":"W4206577522","doi":"10.1073/pnas.2118238119","title":"Skin-resident dendritic cells mediate postoperative pain via CCR4 on sensory neurons","year":2022,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Queen's University","funders":"Canadian Institutes of Health Research","keywords":"CCR4; CCL17; Chemokine; Immunology; Medicine; Immune system; Chemokine receptor; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001795386,0.0003004611,0.0002159826,0.000195968,0.0002018044,0.0003213192,0.0001869666,0.0002732839,0.001715732],"category_scores_gemma":[0.0001621384,0.00009344423,0.0002453484,0.00008161142,0.0002738579,0.0002875781,0.0002846826,0.0005489266,0.0003983207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000217276,"about_ca_system_score_gemma":0.0002815403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002939756,"about_ca_topic_score_gemma":0.000461908,"domain_scores_codex":[0.9998553,0.00003540626,0.00001053144,0.00001216054,0.00002519692,0.00006145237],"domain_scores_gemma":[0.9999312,0.000007954461,0.00001971698,0.000006732052,0.00001282172,0.00002158081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004355561,0.00007023998,0.001093062,0.000114077,0.000009046571,0.0002633121,0.00004116252,0.0001178247,0.9903972,0.0003224187,0.00009327773,0.007042769],"study_design_scores_gemma":[0.0001896698,0.002090155,0.03601095,0.00009141485,0.0001497208,0.001539391,0.0004441377,0.002999824,0.9479227,0.0007716425,0.007765928,0.00002453918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871324,0.005428402,0.004122893,0.0003370672,0.00005601161,0.00005394311,0.0000955144,0.00004557165,0.002728237],"genre_scores_gemma":[0.9937668,0.002356725,0.001359162,0.00007598429,0.00003099905,0.00005063827,0.00006176683,0.000005751158,0.002292192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001715732,"threshold_uncertainty_score":0.005739629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0362818065904435,"score_gpt":0.3013955268254023,"score_spread":0.2651137202349588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}