{"id":"W4206612011","doi":"10.2174/277243281701211223102125","title":"Special issue: Innovations in Early Clinical Drug Evaluation","year":2022,"lang":"en","type":"editorial","venue":"Current Reviews in Clinical and Experimental Pharmacology","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Drug; Computer science; Medicine; Engineering ethics; Pharmacology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02851156,0.007156346,0.01214023,0.01075143,0.00475031,0.01693537,0.006494912,0.02820159,0.02740032],"category_scores_gemma":[0.08471873,0.002592672,0.006171475,0.004700741,0.004964892,0.007745204,0.003317658,0.03466933,0.01508762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00784442,"about_ca_system_score_gemma":0.007805154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002334577,"about_ca_topic_score_gemma":0.007689208,"domain_scores_codex":[0.9778074,0.005731706,0.003453598,0.002409019,0.009526992,0.001071358],"domain_scores_gemma":[0.8921514,0.05506442,0.007799506,0.003157219,0.03122921,0.01059824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004055297,0.00001792735,0.0000174758,0.0003453608,0.00003097991,0.00003273245,0.000006119506,0.00002186319,0.00002182128,0.000234046,0.9952166,0.004014455],"study_design_scores_gemma":[0.0003959006,0.00007009801,0.0005599947,0.001968214,0.0002594219,0.0002387358,0.00004455335,0.0004133304,0.000109436,0.003094124,0.992792,0.00005413986],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.00001041511,0.00747242,0.0001136126,0.01987849,0.9716756,0.00002325647,0.00004574086,0.0000398264,0.0007405099],"genre_scores_gemma":[0.0001144306,0.003029314,0.00009148886,0.01136557,0.9827632,0.00003089456,0.00002162833,0.00002943198,0.002553982],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.02851156,"threshold_uncertainty_score":0.1507853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5516468508394445,"score_gpt":0.6239042976187232,"score_spread":0.0722574467792787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}