{"id":"W4206616643","doi":"10.3410/f.10227956.12934054","title":"Faculty Opinions recommendation of Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4.","year":2011,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Wellcome Trust","keywords":"CD80; CD86; CD28; Cytotoxic T cell; Endocytosis; Political science; Cell biology; T cell; Chemistry; Immune system; Biology; Receptor; Immunology; CD40; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002823532,0.0005582846,0.0005641454,0.001231861,0.001838531,0.005087777,0.001318603,0.004621421,0.315865],"category_scores_gemma":[0.008434058,0.0003406309,0.0009854335,0.001430863,0.0008645765,0.001987477,0.001491541,0.004021338,0.1321938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003711761,"about_ca_system_score_gemma":0.009548214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006806255,"about_ca_topic_score_gemma":0.01121812,"domain_scores_codex":[0.9970278,0.0001983178,0.0001603257,0.000323571,0.001954702,0.0003352889],"domain_scores_gemma":[0.9871553,0.0005151671,0.0006377225,0.000455383,0.007964089,0.003272331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004808453,0.00002891789,0.0002875628,0.0002169322,0.0000101855,0.0001343397,0.00005317871,0.00004263041,0.001433939,0.002142254,0.9585772,0.0370249],"study_design_scores_gemma":[0.00002215011,0.00003043427,0.0005921992,0.0001366872,0.000009707731,0.0000880064,0.0001041741,0.00005844654,0.0007476828,0.001104051,0.997095,0.00001152837],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"dataset","genre_scores_codex":[0.00277725,0.009989589,0.003666468,0.3327652,0.2456469,0.0005176376,0.00981505,0.00100589,0.393816],"genre_scores_gemma":[0.01857646,0.01795054,0.00363683,0.05862604,0.05510819,0.0001837203,0.0060784,0.000497004,0.8393427],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.315865,"threshold_uncertainty_score":0.9758356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02845898539602804,"score_gpt":0.2931088619874593,"score_spread":0.2646498765914313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}