{"id":"W4206714171","doi":"10.1371/journal.pone.0261723","title":"Effect of short-term hindlimb immobilization on skeletal muscle atrophy and the transcriptome in a low compared with high responder to endurance training model","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto","funders":"National Institutes of Health; Queensland University of Technology; Department of Education and Training; Australian Collaborative Education Network","keywords":"Atrophy; Endurance training; Soleus muscle; Internal medicine; Muscle atrophy; Skeletal muscle; Endocrinology; Transcriptome; Hindlimb; Plantaris muscle; Biology; Medicine; Gene expression; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001454938,0.0004525155,0.000459381,0.0002693338,0.0001386212,0.0002821505,0.0002040675,0.0002054877,0.001273347],"category_scores_gemma":[0.00008681283,0.0001407954,0.0004367434,0.0001466512,0.0002320209,0.0001701183,0.0002645525,0.0007133571,0.0001865469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001716776,"about_ca_system_score_gemma":0.0001732421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005297339,"about_ca_topic_score_gemma":0.001282508,"domain_scores_codex":[0.9998154,0.00001624117,0.00001590652,0.00005659153,0.00003655329,0.00005929582],"domain_scores_gemma":[0.9998528,0.000009346936,0.0000500425,0.00001583717,0.00001372639,0.0000582414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001304257,0.0002399524,0.0006934758,0.00005294202,0.00002316217,0.00004177416,0.00002174859,0.00003608639,0.9961665,0.00001503729,0.00005338362,0.001351782],"study_design_scores_gemma":[0.0001975499,0.0137999,0.0876047,0.0000415707,0.000352151,0.0003598209,0.0002970951,0.00126881,0.8942518,0.0000749223,0.001722113,0.00002967585],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986132,0.000372214,0.0004359754,0.0000463329,0.00002842141,0.00001411452,0.0002640413,0.00003249987,0.000193181],"genre_scores_gemma":[0.9943655,0.0006511627,0.0008605974,0.0001067472,0.00001844664,0.0001147998,0.001114972,0.0000261031,0.00274161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001273347,"threshold_uncertainty_score":0.004259706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01615401310346297,"score_gpt":0.2278350910595103,"score_spread":0.2116810779560473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}