{"id":"W4206737985","doi":"10.1001/jama.288.23.2967","title":"Update: Fatal and Severe Liver Injuries Associated With Rifampin and Pyrazinamide Treatment for Latent Tuberculosis Infection","year":2002,"lang":"en","type":"article","venue":"JAMA","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Health Canada; Centers for Disease Control and Prevention; Washington State University; Kaiser Permanente","keywords":"Medicine; Pyrazinamide; Tuberculosis; Latent tuberculosis; Rifampicin; Internal medicine; Mycobacterium tuberculosis; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002345684,0.0001963038,0.0002046554,0.00008014333,0.0004118808,0.00005600523,0.00003176068,0.0003716525,0.0001540584],"category_scores_gemma":[0.000063801,0.0001643437,0.00004445255,0.0001162064,0.0001217558,0.0002610313,0.0000270443,0.0002959737,0.00002152836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001423978,"about_ca_system_score_gemma":0.00001231054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001882397,"about_ca_topic_score_gemma":0.000508001,"domain_scores_codex":[0.9990609,0.0001755442,0.0001589443,0.0002717963,0.00007248667,0.0002602855],"domain_scores_gemma":[0.9994699,0.0001901643,0.00007025799,0.00007940432,0.00007002213,0.0001202558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002118265,0.001654199,0.3187842,0.0002800925,0.001779861,0.00005026147,0.005915948,0.0002739401,0.01245219,0.001165741,0.004366712,0.6511586],"study_design_scores_gemma":[0.02678333,0.005492658,0.5164704,0.000196524,0.001777643,0.0003083555,0.00021206,0.05590475,0.1831176,0.001506684,0.2065668,0.001663158],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965513,0.0004033736,0.00005666291,0.001200207,0.000200479,0.0007717846,0.0001495073,0.00010086,0.0005657913],"genre_scores_gemma":[0.9964378,0.001933963,0.00007575299,0.0005908562,0.000123976,0.0002017884,0.00005353503,0.00001913099,0.0005631833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6494954,"threshold_uncertainty_score":0.6701741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09098552226784327,"score_gpt":0.3508745833039286,"score_spread":0.2598890610360853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}