{"id":"W4206747988","doi":"10.3389/fcell.2021.716853","title":"Therapeutic Mesenchymal Stem/Stromal Cells: Value, Challenges and Optimization","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Amis de l'Institut Bordet; Université de Montréal; Fonds De La Recherche Scientifique - FNRS; Arthritis Society","keywords":"Mesenchymal stem cell; Stem cell; Stromal cell; Value (mathematics); Cell biology; Biology; Medicine; Cancer research; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001729368,0.0005670022,0.001050945,0.001201014,0.0002716077,0.00184167,0.000652568,0.001221089,0.002070768],"category_scores_gemma":[0.0009355476,0.0002355738,0.0004573381,0.0009516367,0.001171932,0.001698016,0.0007336935,0.002080688,0.0009996541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007471478,"about_ca_system_score_gemma":0.001010166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003791118,"about_ca_topic_score_gemma":0.0006382312,"domain_scores_codex":[0.9993243,0.0001663184,0.00007544977,0.00010485,0.0002729246,0.0000561712],"domain_scores_gemma":[0.9993005,0.0004207376,0.00007062096,0.00001842866,0.000145288,0.00004438201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001498703,0.0001065535,0.0004088075,0.01154383,0.00005789527,0.0004488966,0.0001849445,0.00125538,0.02995022,0.02325122,0.008491576,0.9241509],"study_design_scores_gemma":[0.00003628382,0.0006400524,0.001733984,0.003672725,0.0002488807,0.003596193,0.0005345319,0.001692148,0.02734249,0.02660829,0.9337997,0.00009458725],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00182243,0.9896545,0.003278945,0.002952374,0.0003046406,0.00001445656,0.00003286684,0.00002357849,0.001916048],"genre_scores_gemma":[0.01073205,0.9830616,0.003614553,0.000814638,0.0007574153,0.00002925404,0.00006061931,0.00001208154,0.0009177224],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002070768,"threshold_uncertainty_score":0.009145916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08372819283685533,"score_gpt":0.3177375131122916,"score_spread":0.2340093202754363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}