{"id":"W4206792393","doi":"10.1111/sji.13144","title":"Positive selection of immune repertoires: A short further history","year":2022,"lang":"en","type":"article","venue":"Scandinavian Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Queen's University","keywords":"Immune system; Biology; Context (archaeology); Negative selection; Organism; Selection (genetic algorithm); Antigen; Immunity; Host (biology); Immunology; Evolutionary biology; Genetics; Gene; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007857552,0.0002924606,0.0008829405,0.0006899572,0.000331851,0.000004683749,0.0007256957,0.0002938596,0.006706863],"category_scores_gemma":[0.00009026383,0.0002731475,0.0004665827,0.0003134342,0.0007864079,0.0001526404,0.0002705064,0.00143993,0.00005141933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008071545,"about_ca_system_score_gemma":0.0003890972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002112083,"about_ca_topic_score_gemma":0.00000914451,"domain_scores_codex":[0.9967318,0.001051874,0.001255449,0.000300887,0.0001089608,0.0005510784],"domain_scores_gemma":[0.9980478,0.0001826759,0.001036983,0.0003615957,0.0003414507,0.00002947739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002256538,0.0005329811,0.003735899,0.00001022834,0.001330344,0.00007764716,0.002259672,0.00001895068,0.9801623,0.0004828957,0.002835158,0.006297365],"study_design_scores_gemma":[0.006465418,0.01234109,0.01884591,0.0001485119,0.0004770368,0.02253191,0.007188117,0.000004279568,0.8032783,0.0006179477,0.1273685,0.0007329383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93914,0.05361277,0.0001113711,0.0004777109,0.004751659,0.0002058081,0.00002817363,0.00003433361,0.00163819],"genre_scores_gemma":[0.9942229,0.0004477783,0.00008724255,0.000109441,0.00005583787,0.00001823821,0.0000371928,0.0000391183,0.004982203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.176884,"threshold_uncertainty_score":0.999972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009152969296014989,"score_gpt":0.2096981044643452,"score_spread":0.2005451351683302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}