{"id":"W4206867083","doi":"","title":"Modulation of mTOR signaling by radiation and rapamycin treatment in canine mast cell cancer cells.","year":2022,"lang":"en","type":"article","venue":"PubMed","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"PI3K/AKT/mTOR pathway; RPTOR; P70-S6 Kinase 1; Cancer research; DNA damage; Cell growth; Chemistry; Biology; Signal transduction; Cell biology; DNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000189004,0.0003561299,0.0004627703,0.0002747854,0.0002413796,0.0002517505,0.0002059198,0.0003612013,0.001125029],"category_scores_gemma":[0.00009423239,0.0001507496,0.000488885,0.0003644519,0.0002090566,0.0002019114,0.0001414596,0.0006358381,0.0004046414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003535196,"about_ca_system_score_gemma":0.0002586115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001106883,"about_ca_topic_score_gemma":0.002405695,"domain_scores_codex":[0.9997796,0.00005170908,0.00002744037,0.00004819499,0.00004842462,0.00004461881],"domain_scores_gemma":[0.9999375,0.00001311622,0.00001800839,0.000009334331,0.00001080764,0.00001119731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004575307,0.0001206977,0.00020373,0.0001509599,0.00001510533,0.00007591992,0.00002871248,0.0001687095,0.996391,0.0001152672,0.000226432,0.002045942],"study_design_scores_gemma":[0.00004836835,0.001224617,0.004493167,0.000007021803,0.00003927574,0.0003429802,0.00003846781,0.0008712093,0.9887898,0.00003518906,0.004101531,0.000008411086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834383,0.007760196,0.002798813,0.0003373025,0.0001376329,0.0001473516,0.002226128,0.0002082681,0.002946035],"genre_scores_gemma":[0.9879338,0.002819364,0.005086239,0.0001115364,0.00002808145,0.0002039701,0.00189475,0.00002239181,0.00189989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001125029,"threshold_uncertainty_score":0.003763616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009165128982677883,"score_gpt":0.2092109200949688,"score_spread":0.200045791112291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}