{"id":"W4206893461","doi":"","title":"AMPK activation stimultes autophagy and ameliorates muscular dystrophy in MDX mice","year":2012,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Autophagy; AMPK; Muscular dystrophy; mdx mouse; Duchenne muscular dystrophy; Medicine; Chemistry; Cell biology; Internal medicine; Protein kinase A; Dystrophin; Biology; Phosphorylation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003152739,0.0007935563,0.001097584,0.0007798572,0.0002887262,0.0006112689,0.0002901066,0.0008523551,0.006383513],"category_scores_gemma":[0.000216288,0.0002686472,0.0006124177,0.0002415133,0.0007124851,0.0004619736,0.0005081076,0.001308689,0.0009732827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003197037,"about_ca_system_score_gemma":0.0002984751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000245838,"about_ca_topic_score_gemma":0.0005896239,"domain_scores_codex":[0.9997523,0.00004097461,0.00003337903,0.00006340343,0.00004571104,0.00006414983],"domain_scores_gemma":[0.999779,0.00003177768,0.00007125636,0.00003123177,0.0000157826,0.0000710082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003856358,0.0002127768,0.0002348195,0.0001993226,0.00002712197,0.0001491475,0.00004377893,0.0001359692,0.9906825,0.0003673208,0.0002882229,0.003802488],"study_design_scores_gemma":[0.0006820869,0.002581837,0.009525488,0.0001149536,0.0001298953,0.0004826459,0.0002047606,0.0008671361,0.9764572,0.0008694811,0.008049822,0.00003461542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989499,0.002753904,0.00214051,0.001155257,0.000264888,0.00004775458,0.001120458,0.0003054325,0.002712767],"genre_scores_gemma":[0.9786537,0.003415656,0.002267796,0.0004521046,0.0001414118,0.0001544152,0.0009928532,0.0001870097,0.01373501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006383513,"threshold_uncertainty_score":0.02135497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286340820835664,"score_gpt":0.2501882731153778,"score_spread":0.2373248649070212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}