{"id":"W4206900988","doi":"10.31032/ijbpas/2021/10.9.5646","title":"RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF TRAMADOL &amp; CAFFEINE IN BULK","year":2021,"lang":"en","type":"article","venue":"International Journal of Biology Pharmacy and Allied Sciences","topic":"Analytical Methods in Pharmaceuticals","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal College of Physicians and Surgeons of Canada","funders":"","keywords":"Tramadol; Caffeine; Chromatography; High-performance liquid chromatography; Chemistry; Pharmacology; Medicine; Internal medicine; Analgesic","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00152556,0.00007109023,0.0001564507,0.00007232332,0.00006341748,0.00003116754,0.000228741,0.00003301196,0.0001090267],"category_scores_gemma":[0.001475814,0.00004709813,0.00003515847,0.00008356901,0.0002612094,0.00008897619,0.00005202743,0.0001295091,2.748922e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002311248,"about_ca_system_score_gemma":0.0001188569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004512332,"about_ca_topic_score_gemma":0.000002464731,"domain_scores_codex":[0.9990544,0.00008302815,0.0004465245,0.0001341172,0.0001818213,0.0001001311],"domain_scores_gemma":[0.9958743,0.00358215,0.0002481742,0.0000325947,0.0002201223,0.00004265347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003043237,0.0001525502,0.00366225,0.0000536806,0.0002825668,0.00001786965,0.0006905179,0.01449688,0.3794869,0.006053564,0.00001723732,0.5947817],"study_design_scores_gemma":[0.001378722,0.0000273667,0.0001648689,0.00007679754,0.00006684297,0.0002147209,0.0001865754,0.163322,0.8103813,0.01199511,0.01208305,0.0001026317],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.800691,0.001160684,0.1939739,0.003635767,0.0002520942,0.00005397409,0.00001232052,0.000003332055,0.0002168983],"genre_scores_gemma":[0.8234361,0.0003567946,0.1759103,0.0001579318,0.00007479095,0.000002769665,0.000003619887,0.000002245431,0.0000555123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5946791,"threshold_uncertainty_score":0.1920606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1172855025584213,"score_gpt":0.4831592216123388,"score_spread":0.3658737190539175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}