{"id":"W4206901398","doi":"10.1158/1078-0432.ccr-21-3284","title":"Targeting Refractory Mantle Cell Lymphoma for Imaging and Therapy Using C-X-C Chemokine Receptor Type 4 Radioligands","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia; Spinal Cord Injury BC","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute","keywords":"Radioligand; CXCR4; Medicine; Mantle cell lymphoma; Cancer research; Chemokine receptor; Biodistribution; Lymphoma; Pathology; Receptor; Internal medicine; Chemokine; Biology; In vivo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003222773,0.0003267923,0.0003368677,0.0002202745,0.0001111236,0.0003510396,0.0003242098,0.000400412,0.0007358873],"category_scores_gemma":[0.0002259997,0.0001142167,0.0002464165,0.0001683176,0.0002771412,0.0001748185,0.0002130715,0.0002649589,0.0002218172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000504204,"about_ca_system_score_gemma":0.0002929019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008489496,"about_ca_topic_score_gemma":0.001191401,"domain_scores_codex":[0.9998662,0.00005273147,0.000006427984,0.00002228838,0.0000300749,0.00002223335],"domain_scores_gemma":[0.9999163,0.00001820621,0.00003493235,0.000009543936,0.000007407019,0.00001358238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00134265,0.0001889982,0.01398219,0.0002826633,0.00006403144,0.0004415861,0.00005156476,0.001601235,0.9603591,0.0001641979,0.0002409043,0.0212809],"study_design_scores_gemma":[0.001080015,0.01311903,0.04719844,0.00006155459,0.0004510939,0.008455019,0.0001357776,0.01563303,0.9033102,0.0002170295,0.01029401,0.00004471649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887572,0.005458472,0.004527127,0.0001321047,0.00001000236,0.00007815343,0.00008120343,0.00007871594,0.0008770288],"genre_scores_gemma":[0.9954845,0.0008807516,0.002959123,0.00009178093,0.0000132166,0.00003795993,0.0001452546,0.00001021409,0.000377209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008489496,"threshold_uncertainty_score":0.003658295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2000450738897895,"score_gpt":0.4930952004430603,"score_spread":0.2930501265532709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}