{"id":"W4206907925","doi":"10.1093/ecco-jcc/jjab232.331","title":"P204 Endotrophin (PRO-C6) is associated with MRE confirmed intestinal strictures and Protein FingerPrint biomarkers of collagen degradation is associated with ulcerations in paediatric Crohn’s disease patients – results from the ImageKids study","year":2022,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Gastroenterology; Internal medicine; Crohn's disease; Fibrosis; Stenosis; Inflammation; Inflammatory bowel disease; Serology; Disease; Pathology; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000574592,0.0003651764,0.0004406623,0.0006835451,0.0002908563,0.0005890836,0.0003551025,0.0004765675,0.001381713],"category_scores_gemma":[0.001168918,0.0002889082,0.0005375707,0.0006309202,0.0003208368,0.0003029578,0.0005592084,0.0004738694,0.0001996629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002295745,"about_ca_system_score_gemma":0.0001839041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001187868,"about_ca_topic_score_gemma":0.001532602,"domain_scores_codex":[0.9995042,0.000114536,0.00007778045,0.0001392842,0.0001080098,0.00005605442],"domain_scores_gemma":[0.9986377,0.0001957054,0.0006728479,0.00009191899,0.0001372986,0.0002644949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007706953,0.00004464844,0.9954644,0.00005613864,0.00008222614,0.0004002515,0.00006178849,0.00003404247,0.00184202,0.00001893773,0.0001477725,0.00107707],"study_design_scores_gemma":[0.00003739601,0.0003253616,0.997133,0.00001524679,0.00005099694,0.001640408,0.00007477501,0.00007055864,0.000366525,0.000010793,0.0002718565,0.000003106446],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986266,0.0004422704,0.00008495706,0.0000228755,0.000004146702,0.00001530479,0.0005738199,0.000003067499,0.0002269184],"genre_scores_gemma":[0.9983264,0.0001458494,0.0002205121,0.00002792774,0.00001081704,0.0000180594,0.001070747,0.000002974292,0.0001767507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001381713,"threshold_uncertainty_score":0.00462234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006999074419451148,"score_gpt":0.2151903566309408,"score_spread":0.2081912822114896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}