{"id":"W4206925700","doi":"10.1016/j.jtct.2022.01.018","title":"Optimal Timing of Allogeneic Stem Cell Transplantation for Primary Myelofibrosis","year":2022,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Myelofibrosis; Medicine; Transplantation; Ruxolitinib; Cohort; Life expectancy; Internal medicine; International Prognostic Scoring System; Confidence interval; Clinical trial; Pediatrics; Myelodysplastic syndromes; Population; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001375743,0.0002945047,0.0005797211,0.0002024901,0.000207869,0.0005453096,0.0005043169,0.0004542893,0.001927776],"category_scores_gemma":[0.005840005,0.0002432243,0.0006381569,0.0001770101,0.0002623063,0.0003968218,0.0003540362,0.0006867118,0.0001896397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000942141,"about_ca_system_score_gemma":0.001452778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003496467,"about_ca_topic_score_gemma":0.004104262,"domain_scores_codex":[0.9996207,0.0001503112,0.00001824229,0.00008201438,0.00004978704,0.00007890669],"domain_scores_gemma":[0.9985716,0.0008277172,0.0002490539,0.00003569819,0.00007539805,0.000240576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002162008,0.0003087988,0.05132059,0.00007708894,0.0001274421,0.0004611735,0.00006333403,0.9171318,0.002330365,0.003288915,0.001587646,0.02114077],"study_design_scores_gemma":[0.0005136987,0.002041207,0.01500725,0.00009905953,0.0002402797,0.0004703039,0.0001273392,0.9688571,0.002354394,0.008546554,0.001693953,0.00004885928],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776949,0.000791222,0.01782875,0.0005900956,0.00007273944,0.0001100227,0.0005828114,0.00007465867,0.002254841],"genre_scores_gemma":[0.9980162,0.0001420929,0.00133676,0.00005874738,0.00000419942,0.00002908772,0.0001784087,0.000004626099,0.0002299761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003496467,"threshold_uncertainty_score":0.00727576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0246060215705951,"score_gpt":0.2511088832027286,"score_spread":0.2265028616321335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}