{"id":"W4206966534","doi":"10.3389/fped.2021.832395","title":"Editorial: New Therapeutic Options for Rare Diseases","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Pediatrics","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto","funders":"","keywords":"Medicine; Intensive care medicine; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003951702,0.003675045,0.002682237,0.002685126,0.002081391,0.004533195,0.002465173,0.008129248,0.033674],"category_scores_gemma":[0.01430992,0.0007743724,0.002209199,0.0006935063,0.001446112,0.004069009,0.001267527,0.01337178,0.02417191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001922036,"about_ca_system_score_gemma":0.001652849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00064475,"about_ca_topic_score_gemma":0.001766853,"domain_scores_codex":[0.997638,0.000438016,0.0002782206,0.000302827,0.001129177,0.000213833],"domain_scores_gemma":[0.9889742,0.003666998,0.0008058791,0.0002912667,0.003932941,0.002328602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003519699,0.00001008585,0.00001618204,0.0001298127,0.000009442053,0.00009688017,0.000005160449,0.00002281803,0.00004324893,0.0002156014,0.9929575,0.00645813],"study_design_scores_gemma":[0.0000573171,0.00002520876,0.0001319327,0.0002957098,0.00003049173,0.000407318,0.00002218136,0.00009861783,0.00009058964,0.0008615229,0.9979661,0.00001309623],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.00003491689,0.005241432,0.0001275217,0.02519233,0.9666892,0.00001711028,0.00005524378,0.00008125027,0.002560955],"genre_scores_gemma":[0.0003500238,0.00407897,0.0001000171,0.0132243,0.9727091,0.00001594918,0.00004289576,0.00003265523,0.009446128],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.033674,"threshold_uncertainty_score":0.1126508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005958535750580178,"score_gpt":0.2376405583142725,"score_spread":0.2316820225636923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}