{"id":"W4206970776","doi":"10.1002/hep.32352","title":"Quantified integrated hepatitis B virus is related to viral activity in patients with chronic hepatitis B","year":2022,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"cccDNA; HBsAg; Hepatitis B virus; Virology; Adefovir; Liver biopsy; Hepatitis B; Medicine; HBeAg; Alanine transaminase; Immunology; Virus; Internal medicine; Biopsy; Lamivudine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004840179,0.0002470627,0.0002460268,0.0006248585,0.0002280116,0.0004290029,0.0001608446,0.0003914706,0.001028801],"category_scores_gemma":[0.002352107,0.0001409586,0.0001982435,0.0006262545,0.0003017937,0.0002952807,0.0003387425,0.0005350755,0.0001386821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001693027,"about_ca_system_score_gemma":0.0001300164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006268029,"about_ca_topic_score_gemma":0.0006743448,"domain_scores_codex":[0.9996529,0.00009933642,0.00005338181,0.00007129535,0.00008395263,0.00003926526],"domain_scores_gemma":[0.9975786,0.0005241918,0.001354026,0.00009985682,0.0001885302,0.0002548713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001310011,0.00001260142,0.9982898,0.000008037719,0.00001751788,0.00001975706,0.00001637952,0.00002936447,0.0004467042,0.000003934618,0.00001273786,0.001012055],"study_design_scores_gemma":[0.000008827095,0.0002231295,0.9986443,0.000005874565,0.00002360461,0.0004061066,0.00004860921,0.0002696643,0.0002671835,0.00001606135,0.00008434823,0.000002279338],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992033,0.0003812685,0.0001568777,0.00001644225,0.000002227924,0.000005458838,0.0000731338,0.000003797214,0.0001575197],"genre_scores_gemma":[0.9997091,0.00004260176,0.0001045909,0.000007138287,0.000004637642,0.000003463893,0.00009554111,7.134213e-7,0.00003223893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001028801,"threshold_uncertainty_score":0.003441691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0132213208287719,"score_gpt":0.2630618099153962,"score_spread":0.2498404890866243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}