{"id":"W4206992185","doi":"10.3389/fnagi.2021.802501","title":"Episodic Memory Impairment Mediates the Loss of Awareness in Mild Cognitive Impairment","year":2022,"lang":"en","type":"article","venue":"Frontiers in Aging Neuroscience","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; Houston Methodist Research Institute; Wake Forest School of Medicine; Medical School, University of Michigan; Canadian Institutes of Health Research; University of California, Los Angeles; National Institutes of Health; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Genentech; University of South Florida; Novartis Pharmaceuticals Corporation; Georgetown University; IXICO; University of Pittsburgh; Vanderbilt University Medical Center; University of Texas Southwestern Medical Center; Johns Hopkins University; York University; University of Rochester; Pfizer; Northwestern University; Biogen; BioClinica; F. Hoffmann-La Roche; Bristol-Myers Squibb; Cleveland Clinic; Emory University; University of Pennsylvania; University of California, San Diego; Yale University; Vanderbilt University; Rush University; Ohio State University; University of Southern California; U.S. Department of Defense; Eli Lilly and Company; Jewish General Hospital; NYU Langone Medical Center; Alzheimer's Association; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics","keywords":"Cognitive impairment; Episodic memory; Memory impairment; Psychology; Cognition; Cognitive psychology; Neuroscience; Developmental psychology; Audiology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001762414,0.0001856225,0.0003400978,0.0006116333,0.0002682028,0.00002648311,0.0004725656,0.00002457936,0.00008211766],"category_scores_gemma":[0.0002051943,0.0001471541,0.00009561406,0.00159243,0.0006463137,0.0001343357,0.0004904292,0.0005392323,0.000001970588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000274759,"about_ca_system_score_gemma":0.0003995393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001766969,"about_ca_topic_score_gemma":0.00001229397,"domain_scores_codex":[0.9967303,0.0004260277,0.0004295043,0.0005497558,0.001210604,0.0006537861],"domain_scores_gemma":[0.9992406,0.0001552114,0.0001319329,0.0002768676,0.00007097138,0.0001243843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000274694,0.000820623,0.9921294,0.00008276531,0.000007940072,0.000323097,0.001741039,0.0001871642,0.00116735,0.000007519376,0.0008007971,0.002457584],"study_design_scores_gemma":[0.002969836,0.0009400923,0.9753971,0.0001624061,0.00003184452,0.00005425363,0.007733305,0.005021649,0.007112072,0.0001955608,0.0002183687,0.0001634872],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944057,0.0005577641,0.0006215909,0.00184705,0.001007643,0.001164405,0.00002808349,0.0000245753,0.0003431308],"genre_scores_gemma":[0.9976621,0.000164328,0.00009883921,0.001269504,0.00002659112,0.0003445611,0.000009959615,0.00001711496,0.0004070632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0167323,"threshold_uncertainty_score":0.6000769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02064826468267844,"score_gpt":0.3067103968706298,"score_spread":0.2860621321879514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}