{"id":"W4207009241","doi":"10.1016/j.devcel.2021.12.022","title":"Early human embryonic development: Blastocyst formation to gastrulation","year":2022,"lang":"en","type":"review","venue":"Developmental Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":203,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Gairdner Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Blastocyst; Biology; Embryonic stem cell; Embryogenesis; Gastrulation; Embryo; Cell biology; Stem cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003888968,0.0004987668,0.0005833332,0.0003589911,0.0004675871,0.000086974,0.000657303,0.0002636407,0.000384102],"category_scores_gemma":[0.00001815546,0.0005220608,0.0002138078,0.0003920895,0.00002713523,0.00001241989,0.0009885158,0.0003314321,0.0009522438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006142691,"about_ca_system_score_gemma":0.0006818476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007844515,"about_ca_topic_score_gemma":0.00002750503,"domain_scores_codex":[0.9972335,0.0001765654,0.0006907514,0.0007276012,0.0005806005,0.0005909962],"domain_scores_gemma":[0.9991106,0.0000158707,0.0002648472,0.0003378905,0.00004476199,0.0002259717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005085176,0.0002466477,0.00005336218,0.01113311,0.0002538512,0.00004562159,0.0005478356,0.00001749055,0.01350172,0.000008936228,0.008770891,0.9653697],"study_design_scores_gemma":[0.0002372202,0.0001247203,0.00008209941,0.0004150706,0.00003420095,0.00005706139,0.00003795947,7.708005e-7,0.003408679,9.771433e-7,0.9950213,0.0005798987],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01748054,0.9623675,0.0005340917,0.00001011438,0.0003848508,0.003289133,0.00009717342,0.00007456913,0.01576207],"genre_scores_gemma":[0.001334579,0.9624536,0.003941701,0.00007809973,0.0001876726,0.001138832,0.01119819,0.0002074469,0.01945991],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9862505,"threshold_uncertainty_score":0.9998257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04309855221222619,"score_gpt":0.3043929333744841,"score_spread":0.2612943811622579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}