{"id":"W4207047969","doi":"10.1161/circinterventions.121.010802","title":"Autologous CD34+ Stem Cell Therapy Increases Coronary Flow Reserve and Reduces Angina in Patients With Coronary Microvascular Dysfunction","year":2022,"lang":"en","type":"article","venue":"Circulation Cardiovascular Interventions","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health","keywords":"Coronary flow reserve; Angina; Fractional flow reserve; Coronary artery disease; Stem-cell therapy; Ischemia; Stem cell; Stable angina; Microcirculation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001217305,0.000510681,0.0006633056,0.000144249,0.0001712848,0.0003106321,0.0002300717,0.0003440063,0.002602292],"category_scores_gemma":[0.0006611805,0.0001540772,0.000340504,0.0001527405,0.0003155545,0.0001986828,0.0002176895,0.0007029239,0.0002409264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001922073,"about_ca_system_score_gemma":0.0004412311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001639952,"about_ca_topic_score_gemma":0.0005511002,"domain_scores_codex":[0.9997149,0.0001531313,0.00002121965,0.00003690738,0.00003672113,0.00003709613],"domain_scores_gemma":[0.9997064,0.0000692055,0.0000807668,0.00001316718,0.0000224381,0.0001079122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5404487,0.048893,0.07574056,0.001926402,0.001951053,0.0003315676,0.0003567543,0.001936012,0.1008174,0.000313895,0.003403117,0.2238815],"study_design_scores_gemma":[0.2318356,0.6003273,0.1540496,0.0001481636,0.0008916499,0.0004129525,0.0001324754,0.001472282,0.00737823,0.0002297031,0.003096995,0.00002503713],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976473,0.001130811,0.0001415928,0.0001096637,0.00001917879,0.0003451908,0.00008094979,0.00001300515,0.000512348],"genre_scores_gemma":[0.9977387,0.0005003788,0.0005765962,0.0002027134,0.00005821134,0.0003676872,0.0001940263,0.000001988954,0.0003597903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002602292,"threshold_uncertainty_score":0.008705497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03080385949232391,"score_gpt":0.2571050374661566,"score_spread":0.2263011779738328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}