{"id":"W4207054094","doi":"10.3390/toxins14020079","title":"Chemical Synthesis of a Functional Fluorescent-Tagged α-Bungarotoxin","year":2022,"lang":"en","type":"article","venue":"Toxins","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal; Université de Montréal; Montreal Heart Institute","funders":"Association Nationale de la Recherche et de la Technologie; Federación Española de Enfermedades Raras; Fondation Leducq; Conseil Régional des Pays de la Loire; Agence Nationale de la Recherche","keywords":"Bungarotoxin; Fluorescence; Peptide; Biochemistry; Fluorophore; Nicotinic agonist; Chemistry; Acetylcholine receptor; Snake venom; Venom; Biophysics; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002764877,0.0003911736,0.0003008581,0.000188494,0.0001922176,0.0001948421,0.0002955823,0.000459552,0.001404491],"category_scores_gemma":[0.0002003045,0.0001828083,0.00029068,0.0003089955,0.0001676142,0.0003056985,0.0002886788,0.0006656452,0.0009736258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003172903,"about_ca_system_score_gemma":0.0002777104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002755357,"about_ca_topic_score_gemma":0.0003292202,"domain_scores_codex":[0.9998517,0.00001772504,0.00001979197,0.00003041272,0.00004890634,0.00003152594],"domain_scores_gemma":[0.9998981,0.00001326877,0.00001951045,0.00001542648,0.00002746467,0.00002620462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000120204,0.00001166513,0.00002796913,0.00005610069,0.000003655992,0.00004638202,0.00001270939,0.0001250668,0.9981869,0.000180136,0.00003780922,0.001299547],"study_design_scores_gemma":[0.00001451577,0.0002777231,0.0006988354,0.00001369691,0.00001890115,0.0003350891,0.00001207239,0.0009001619,0.9906549,0.0001006186,0.00696331,0.00001017357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8638749,0.005184855,0.1193682,0.0003787379,0.0002463791,0.0005937143,0.002005982,0.0005591039,0.007788246],"genre_scores_gemma":[0.8998806,0.005450124,0.08070813,0.0002803543,0.00003363214,0.0003163158,0.003330368,0.0001253816,0.009875147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001404491,"threshold_uncertainty_score":0.004698515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01184203040517594,"score_gpt":0.2157349433202855,"score_spread":0.2038929129151095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}