{"id":"W4210241596","doi":"10.1101/2022.02.03.478032","title":"Proteostasis in ice: The role of heat shock proteins and ubiquitin in the freeze tolerance of the intertidal mussel, <i>Mytilus trossulus</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Universities Space Research Association","keywords":"Intertidal zone; Biology; Mussel; Mytilus; Hsp70; Heat shock protein; Ubiquitin; Ecology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000955074,0.000171284,0.0001923148,0.0002096867,0.0003372951,0.0002969245,0.0001279534,0.0002542577,0.0005683337],"category_scores_gemma":[0.00007932497,0.00009652746,0.0002202165,0.0001348867,0.0002378059,0.0002041823,0.000210957,0.0001824861,0.00008475025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004240891,"about_ca_system_score_gemma":0.0001784752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00489446,"about_ca_topic_score_gemma":0.01072234,"domain_scores_codex":[0.9999456,0.00000423413,0.000003543853,0.00002057879,0.0000123993,0.00001362749],"domain_scores_gemma":[0.9999205,0.000006144989,0.00003215377,0.000005097198,0.00001659385,0.0000195423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002470662,0.00002130684,0.01566623,0.00004098448,0.00001453255,0.00004209302,0.00006022128,0.00009305984,0.9828537,0.00001852186,0.00002202779,0.0009202317],"study_design_scores_gemma":[0.000008313359,0.0004798378,0.8767099,0.0000139123,0.00002668785,0.0001434981,0.0002917095,0.0005093162,0.12126,0.00005025377,0.0004979054,0.000008743614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994049,0.0002159058,0.00009942265,0.00001333128,0.000001352843,0.00000353237,0.0001078271,0.000003079599,0.0001505392],"genre_scores_gemma":[0.9992169,0.00009039533,0.0001486983,0.00001797528,0.000001173242,0.000007986993,0.0001485693,0.00000157711,0.0003666114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00489446,"threshold_uncertainty_score":0.009731948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00900519086825704,"score_gpt":0.1982004835831248,"score_spread":0.1891952927148678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}