{"id":"W4210281111","doi":"10.3389/fcell.2022.837406","title":"Running ‘LAPS’ Around nLD: Nuclear Lipid Droplet Form and Function","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Lipid droplet; Cell biology; Nuclear pore; Sterol regulatory element-binding protein; Chromatin; Nuclear protein; Biogenesis; Transcription factor; Biology; Nucleoplasm; Promyelocytic leukemia protein; Lipid metabolism; Biochemistry; Chemistry; Cytoplasm; Gene; Nucleolus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002872704,0.0005087242,0.0009178673,0.001097331,0.0002615666,0.00127819,0.0005159301,0.0007181903,0.001917837],"category_scores_gemma":[0.0003247741,0.0002445166,0.000524959,0.001055442,0.0004511541,0.001690487,0.0005711186,0.001008242,0.001262331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006239907,"about_ca_system_score_gemma":0.0008588306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005233088,"about_ca_topic_score_gemma":0.0004818945,"domain_scores_codex":[0.9998387,0.000017088,0.00003385429,0.00004818649,0.00003769152,0.00002443566],"domain_scores_gemma":[0.9998871,0.00002523379,0.00002776316,0.000006151738,0.00003418217,0.00001953043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003864745,0.00003931478,0.001626676,0.02264169,0.0002104546,0.001547479,0.0006684262,0.0008248414,0.1548448,0.01608789,0.0252971,0.7758248],"study_design_scores_gemma":[0.000007743104,0.0001304309,0.003258654,0.001165697,0.0001162161,0.003475331,0.0002389517,0.0001911803,0.02271377,0.003055298,0.9655995,0.00004729517],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003417054,0.9905234,0.001974697,0.0007803888,0.0006076961,0.00001262557,0.0001804506,0.00007911318,0.002424565],"genre_scores_gemma":[0.0121958,0.9810264,0.002188728,0.0005146306,0.0005158787,0.00001632937,0.0004807359,0.00002101693,0.00304054],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001917837,"threshold_uncertainty_score":0.006415784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01463200649992639,"score_gpt":0.2300075969449269,"score_spread":0.2153755904450005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}