{"id":"W4210281111","doi":"10.3389/fcell.2022.837406","title":"Running ‘LAPS’ Around nLD: Nuclear Lipid Droplet Form and Function","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Lipid droplet; Cell biology; Nuclear pore; Sterol regulatory element-binding protein; Chromatin; Nuclear protein; Biogenesis; Transcription factor; Biology; Nucleoplasm; Promyelocytic leukemia protein; Lipid metabolism; Biochemistry; Chemistry; Cytoplasm; Gene; Nucleolus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002612916,0.0003857996,0.0008002222,0.0001962009,0.0002074749,0.00003046239,0.0001852675,0.00048127,0.00007004898],"category_scores_gemma":[0.00002141586,0.0003279121,0.0001072923,0.0001273874,0.0001474925,0.000007010043,0.0004817833,0.0002514955,0.000008164016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005446943,"about_ca_system_score_gemma":0.0001504176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001128762,"about_ca_topic_score_gemma":0.000006172405,"domain_scores_codex":[0.9983624,0.0001014368,0.0004234165,0.0006863592,0.00006950401,0.0003568366],"domain_scores_gemma":[0.9995594,0.00001782249,0.000165603,0.0001550947,0.000007879767,0.0000941958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005223367,0.0000422373,0.0006497455,0.000998891,0.00008618925,0.000003220829,0.00008444289,2.233722e-8,0.0006058055,0.00001288292,0.004910798,0.9925535],"study_design_scores_gemma":[0.000309728,0.00011731,0.0000415565,0.0001078977,0.00009908715,0.00004484645,0.0004402879,0.000001254392,0.0001658547,0.00002553544,0.9982186,0.0004280404],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005501383,0.9906588,0.00006038903,0.000004798657,0.001465637,0.000309752,0.00004587235,0.00001391405,0.001939479],"genre_scores_gemma":[0.0004893342,0.993576,0.00390141,0.0001529855,0.0003031649,0.00005871747,0.0008942001,0.00004393833,0.0005801957],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9933078,"threshold_uncertainty_score":0.9999173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01463200649992639,"score_gpt":0.2300075969449269,"score_spread":0.2153755904450005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}