{"id":"W4210312677","doi":"10.1007/s11033-022-07183-w","title":"Evaluating the effects of sodium glucose co-transporter -2 inhibitors from a renin–angiotensin–aldosterone system perspective in patients infected with COVID-19: contextualizing findings from the dapagliflozin in respiratory failure in patients with COVID-19 study","year":2022,"lang":"en","type":"review","venue":"Molecular Biology Reports","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Qingdao University of Science and Technology; Qatar University","keywords":"Dapagliflozin; Medicine; Renin–angiotensin system; Diabetes mellitus; Coronavirus disease 2019 (COVID-19); Type 2 Diabetes Mellitus; Pharmacology; Disease; Internal medicine; Endocrinology; Infectious disease (medical specialty); Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001619105,0.0008604144,0.002655859,0.0006620676,0.0001542907,0.00003096067,0.0002946223,0.000365567,0.0000235241],"category_scores_gemma":[0.001748579,0.0004890049,0.000276386,0.001073765,0.0002922633,0.00006385476,0.0002431189,0.0008888215,0.000001409271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002302887,"about_ca_system_score_gemma":0.001061512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005086335,"about_ca_topic_score_gemma":0.002618831,"domain_scores_codex":[0.9925101,0.002841609,0.001745758,0.001512586,0.0008153078,0.0005746117],"domain_scores_gemma":[0.9955169,0.001229904,0.001588499,0.001293709,0.0001605189,0.000210459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009518097,0.00157701,0.9790645,0.001522081,0.002128994,0.004287115,0.005766885,0.00001315478,0.00002670045,0.000007417365,0.0000946263,0.004559685],"study_design_scores_gemma":[0.07320438,0.03625752,0.7704828,0.03416373,0.0182377,0.00004343828,0.01002977,0.00001013719,0.0001103587,0.00006421433,0.05449792,0.002897986],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8536345,0.1331201,0.00002341691,0.00009872373,0.0002268005,0.01273066,0.00009647277,0.0000557643,0.00001354989],"genre_scores_gemma":[0.9897139,0.003597675,0.00007307468,0.001193787,0.00003751296,0.002078966,0.00314585,0.0001511056,0.000008142309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2085817,"threshold_uncertainty_score":0.9997562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02825611378280104,"score_gpt":0.3373203636237574,"score_spread":0.3090642498409564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}