{"id":"W4210318387","doi":"10.1002/adhm.202102366","title":"Immunomodulatory Microgels Support Proregenerative Macrophage Activation and Attenuate Fibroblast Collagen Synthesis","year":2022,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute on Deafness and Other Communication Disorders","keywords":"Self-healing hydrogels; Fibroblast; Wound healing; Hyaluronic acid; Scars; Macrophage; Cell biology; Materials science; Connective tissue; Myofibroblast; Chemistry; Immunology; In vitro; Medicine; Fibrosis; Pathology; Biology; Biochemistry; Anatomy; Polymer chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006798152,0.0002107695,0.00007881488,0.0001112202,0.00005650305,0.0001540569,0.0000558577,0.0001519995,0.0007852546],"category_scores_gemma":[0.00006940287,0.00005957612,0.00009258291,0.00003970946,0.0001106907,0.00009700027,0.0000697908,0.0001320752,0.000125077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009763353,"about_ca_system_score_gemma":0.0000619491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002339031,"about_ca_topic_score_gemma":0.0005116589,"domain_scores_codex":[0.9999614,0.000006547978,0.00000290567,0.000007591696,0.00001027865,0.00001136108],"domain_scores_gemma":[0.9999357,0.00001983553,0.00001894751,0.00000503162,0.000008305301,0.00001213705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003701233,0.00001161754,0.00003308895,0.00001984601,0.000001386919,0.00001482424,0.000004775209,0.00004250143,0.9989998,0.00001925593,0.00001244088,0.0008034298],"study_design_scores_gemma":[0.00000675569,0.0001644925,0.0006794649,0.000002984623,0.000005182653,0.00002900748,0.000009225466,0.0002750503,0.9979625,0.000009031832,0.000854742,0.000001493239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952128,0.001079721,0.002286774,0.00004300852,0.00002931486,0.00001814457,0.00009002012,0.00005227733,0.001187974],"genre_scores_gemma":[0.9959954,0.000411194,0.002004541,0.000036659,0.00001100606,0.00001800812,0.00005730909,0.00001020689,0.001455552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007852546,"threshold_uncertainty_score":0.002626956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01591613456450311,"score_gpt":0.2862673778040973,"score_spread":0.2703512432395942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}