{"id":"W4210318387","doi":"10.1002/adhm.202102366","title":"Immunomodulatory Microgels Support Proregenerative Macrophage Activation and Attenuate Fibroblast Collagen Synthesis","year":2022,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute on Deafness and Other Communication Disorders","keywords":"Self-healing hydrogels; Fibroblast; Wound healing; Hyaluronic acid; Scars; Macrophage; Cell biology; Materials science; Connective tissue; Myofibroblast; Chemistry; Immunology; In vitro; Medicine; Fibrosis; Pathology; Biology; Biochemistry; Anatomy; Polymer chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002869569,0.0002078373,0.000453072,0.00009794294,0.0005841461,0.00002746616,0.00005605113,0.00006333263,0.0004046308],"category_scores_gemma":[0.00004446613,0.0001974614,0.00003899706,0.0001283918,0.00004882538,0.00009739565,0.00009122993,0.00009056995,0.00002337501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004006506,"about_ca_system_score_gemma":0.000239013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002765429,"about_ca_topic_score_gemma":0.0000107316,"domain_scores_codex":[0.9983731,0.000240582,0.0003949407,0.0004081064,0.0002341951,0.0003490716],"domain_scores_gemma":[0.9991899,0.00007143613,0.0002003932,0.0002875304,0.00009997501,0.0001507612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001028269,0.0001244629,0.001145867,0.0004864189,0.000100608,0.00008616393,0.0009808982,0.00001742114,0.9874124,0.0001627195,0.0001745023,0.008280294],"study_design_scores_gemma":[0.001457785,0.0009561584,0.0160425,0.0001776415,0.00005329565,0.0001706316,0.000595577,0.000002971961,0.9758551,0.0002027765,0.004278544,0.0002069995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948223,0.0003203221,0.00001202884,0.002801182,0.0002441294,0.001144562,0.0004930208,0.00009111084,0.00007139797],"genre_scores_gemma":[0.9957232,0.00008686649,0.001479859,0.0008229238,0.00009216665,0.0007001472,0.0003023863,0.00005073814,0.0007416594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01489663,"threshold_uncertainty_score":0.8052244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01591613456450311,"score_gpt":0.2862673778040973,"score_spread":0.2703512432395942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}