{"id":"W4210340087","doi":"10.3390/ijms23031476","title":"ARPC1B Is Associated with Lethal Prostate Cancer and Its Inhibition Decreases Cell Invasion and Migration In Vitro","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Calgary","funders":"Canadian Cancer Society; Prostate Cancer Foundation","keywords":"Erg; Prostate cancer; PTEN; DU145; Cancer research; Biology; Metastasis; Prostate; Cancer; Immunohistochemistry; Medicine; PI3K/AKT/mTOR pathway; Internal medicine; Immunology; Signal transduction; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002358725,0.0004971434,0.0003992723,0.0004824235,0.0002658571,0.0002732161,0.0002359927,0.0002285112,0.002960268],"category_scores_gemma":[0.0001421059,0.0002545129,0.0003963779,0.0003892404,0.0001757412,0.00008824349,0.0001846669,0.0008961022,0.0007159393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002488431,"about_ca_system_score_gemma":0.0002952323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001328076,"about_ca_topic_score_gemma":0.002234125,"domain_scores_codex":[0.9996281,0.00008675687,0.00003052911,0.00004044597,0.0001258676,0.00008841005],"domain_scores_gemma":[0.9998734,0.00002459674,0.00002695926,0.00001757042,0.00001423914,0.00004334369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003070017,0.0002481409,0.0003201898,0.000106346,0.00003069429,0.00009340635,0.00001913729,0.00007364576,0.9952762,0.0001187816,0.0006100408,0.002796229],"study_design_scores_gemma":[0.00008967439,0.001643147,0.0166878,0.00002091017,0.00006182469,0.001133811,0.00003012546,0.001885166,0.9672583,0.00007704722,0.01110265,0.000009496425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745026,0.01461529,0.003246423,0.0004673919,0.0001507551,0.00006820937,0.001001633,0.0003417452,0.005605856],"genre_scores_gemma":[0.9800861,0.005608122,0.002138342,0.0001566927,0.00004136755,0.0001270066,0.003099269,0.00004298715,0.008700164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002960268,"threshold_uncertainty_score":0.009903073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02117813787837569,"score_gpt":0.3089733291191845,"score_spread":0.2877951912408088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}