{"id":"W4210340286","doi":"10.1002/alz.050014","title":"Transcriptome analysis highlights common pathways between Alzheimer’s disease, dementia with Lewy bodies and Parkinson’s disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Dementia with Lewy bodies; Biology; Dementia; Transcriptome; Disease; Genetic association; Genome-wide association study; Linkage disequilibrium; Correlation; False discovery rate; Parkinson's disease; Genetics; Bioinformatics; Gene; Medicine; Pathology; Gene expression; Single-nucleotide polymorphism; Haplotype; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002688679,0.0001870567,0.0002943231,0.0006862136,0.000345861,0.0004478024,0.0000882461,0.0001511712,0.001471027],"category_scores_gemma":[0.0004288574,0.00008881781,0.0006124586,0.001036026,0.0001665662,0.0001866622,0.0003227216,0.0002636347,0.0002020641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001867475,"about_ca_system_score_gemma":0.0002619287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009999946,"about_ca_topic_score_gemma":0.001559159,"domain_scores_codex":[0.9998185,0.00003113391,0.00001409173,0.00006854012,0.00003121106,0.00003659006],"domain_scores_gemma":[0.9997404,0.0001026379,0.00007760262,0.00001734265,0.00003415025,0.00002783267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00153491,0.0001387465,0.3386241,0.0008356157,0.0005537256,0.001003381,0.0006895415,0.003212244,0.6022689,0.001504244,0.002211878,0.04742274],"study_design_scores_gemma":[0.00001294749,0.0001772517,0.9736633,0.00002807548,0.0002129529,0.0007126125,0.0003455547,0.005354131,0.01551227,0.001297348,0.002666985,0.00001667795],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802037,0.00160552,0.009195349,0.0001910635,0.00001920545,0.00002046954,0.007438248,0.0001795675,0.001146865],"genre_scores_gemma":[0.9807344,0.000696019,0.01118207,0.0001104281,0.00001621367,0.00006240957,0.006499373,0.00003681677,0.000662161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001471027,"threshold_uncertainty_score":0.004921019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03331668867324963,"score_gpt":0.2648491064120347,"score_spread":0.2315324177387851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}