{"id":"W4210359335","doi":"10.1016/j.ymgme.2021.11.167","title":"Severe kidney dysfunction in the mouse model of sialidosis reveals novel role of neuraminidase 1 in reabsorption process","year":2022,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Centre Hospitalier Universitaire Sainte-Justine; McGill University","funders":"","keywords":"Reabsorption; Neuraminidase; Process (computing); Kidney; Biology; Cell biology; Endocrinology; Biochemistry; Computer science; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000295652,0.001330943,0.0007574878,0.001241744,0.0003445203,0.0006315536,0.0005386136,0.001119321,0.001927503],"category_scores_gemma":[0.0002141857,0.0006273626,0.0008703794,0.0004311331,0.0007758703,0.0008252988,0.0004646963,0.002067207,0.0004307983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005317879,"about_ca_system_score_gemma":0.0005127515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007989336,"about_ca_topic_score_gemma":0.0008678521,"domain_scores_codex":[0.9996983,0.00003498023,0.00003610626,0.0000867465,0.0000822752,0.00006168566],"domain_scores_gemma":[0.999588,0.0000304239,0.0001431417,0.00004235105,0.00003356915,0.0001625657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000893174,0.0000947118,0.0007310603,0.00008611543,0.00003690384,0.0006470794,0.00003400185,0.0001917791,0.9958729,0.0003819391,0.0001008362,0.0009293906],"study_design_scores_gemma":[0.0001704518,0.0009889482,0.02359147,0.00003267732,0.0002723527,0.004195393,0.0001440285,0.003558868,0.9629402,0.001335483,0.002728966,0.00004111283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889122,0.001717302,0.00632241,0.0003811299,0.00009280317,0.00004339487,0.001116753,0.0003279773,0.001086006],"genre_scores_gemma":[0.9895103,0.001551445,0.003050676,0.0001626949,0.00002301078,0.00007686788,0.001040471,0.00008549037,0.004499088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001927503,"threshold_uncertainty_score":0.00644809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01302759339054739,"score_gpt":0.2551247624918986,"score_spread":0.2420971691013512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}