{"id":"W4210366328","doi":"10.2196/preprints.10826","title":"Varenicline and Bupropion for Long-Term Smoking Cessation (the MATCH Study): Protocol for a Real-World, Pragmatic, Randomized Controlled Trial (Preprint)","year":2018,"lang":"en","type":"preprint","venue":"","topic":"Smoking Behavior and Cessation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Varenicline; Smoking cessation; Medicine; Bupropion; Randomized controlled trial; Medical prescription; Family medicine; Nicotine replacement therapy; Cotinine; Psychiatry; Nicotine; Internal medicine; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05826764,0.007303324,0.01006145,0.003235037,0.004492358,0.004716728,0.003681246,0.008533774,0.141617],"category_scores_gemma":[0.04427792,0.005113761,0.005801044,0.004070267,0.003861133,0.005162301,0.002670299,0.01022476,0.0274573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005539571,"about_ca_system_score_gemma":0.01920409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002377689,"about_ca_topic_score_gemma":0.00530103,"domain_scores_codex":[0.9604583,0.02771929,0.004274781,0.002257619,0.002707543,0.002582384],"domain_scores_gemma":[0.9813157,0.006122084,0.003472034,0.003009474,0.003611635,0.002469181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7172064,0.01974808,0.00108864,0.05617377,0.00274338,0.0007970333,0.001118612,0.004512342,0.004372782,0.01314491,0.1008991,0.07819496],"study_design_scores_gemma":[0.8411622,0.02517464,0.00279691,0.01047514,0.0009431819,0.0001966422,0.0002941371,0.003724205,0.001895054,0.006540736,0.1065285,0.0002686671],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0003568462,0.00008438883,0.0008311808,0.0001009769,0.0001719345,0.9975446,0.0005828574,0.00005618711,0.0002709877],"genre_scores_gemma":[0.0003729431,0.00005327888,0.001186449,0.00008878971,0.00002682185,0.9980128,0.00008396834,0.000004302458,0.0001707257],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.141617,"threshold_uncertainty_score":0.4737561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05175844527548616,"score_gpt":0.4053348677413751,"score_spread":0.3535764224658889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}