{"id":"W4210367390","doi":"10.3390/cells11030448","title":"Characterization of Gfat1 (zeppelin) and Gfat2, Essential Paralogous Genes Which Encode the Enzymes That Catalyze the Rate-Limiting Step in the Hexosamine Biosynthetic Pathway in Drosophila melanogaster","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome British Columbia; York University; Allergan (Canada); Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Drosophila melanogaster; Melanogaster; Gene; Genetics; Euchromatin; Biochemistry; Heterochromatin; Chromatin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006327221,0.0001296857,0.0001290937,0.00003832064,0.0001391712,0.00002719337,0.000263034,0.00006510438,0.0000218363],"category_scores_gemma":[0.000009731611,0.00007799472,0.00004976836,0.0001585854,0.00009180843,0.00000640048,0.00008912295,0.0001479549,9.460472e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007114552,"about_ca_system_score_gemma":0.00003355033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000564459,"about_ca_topic_score_gemma":0.0004068372,"domain_scores_codex":[0.9988947,0.0003026437,0.0002394742,0.0002375462,0.0001467458,0.0001789114],"domain_scores_gemma":[0.9995027,0.00004663502,0.000116795,0.0002940759,0.00002400292,0.00001585528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005787253,0.00005234776,0.003534988,0.00001775176,0.000009546544,0.000006654895,0.001046155,0.0001171137,0.9945959,0.00006004021,0.000003506076,0.0004981013],"study_design_scores_gemma":[0.0004087068,0.0000860548,0.01274238,0.00001205625,0.00001984763,0.0000183184,0.00124596,0.0006451306,0.9795775,0.00002537878,0.005093663,0.000124988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972751,0.0009217146,0.0004096664,0.0008019677,0.0001372938,0.000334968,0.00005789439,0.000003074576,0.00005836573],"genre_scores_gemma":[0.9978087,0.0004071994,0.000008019285,0.0001766849,0.00008752629,0.00004493367,0.001388564,0.00001415944,0.00006419248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01501841,"threshold_uncertainty_score":0.3180532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009292628025787038,"score_gpt":0.1981367419846506,"score_spread":0.1888441139588635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}