{"id":"W4210367390","doi":"10.3390/cells11030448","title":"Characterization of Gfat1 (zeppelin) and Gfat2, Essential Paralogous Genes Which Encode the Enzymes That Catalyze the Rate-Limiting Step in the Hexosamine Biosynthetic Pathway in Drosophila melanogaster","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome British Columbia; York University; Allergan (Canada); Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Drosophila melanogaster; Melanogaster; Gene; Genetics; Euchromatin; Biochemistry; Heterochromatin; Chromatin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007219573,0.0002846381,0.0001050717,0.0002576018,0.0001732087,0.0001971425,0.0001904711,0.0002440813,0.0008286704],"category_scores_gemma":[0.0001067576,0.0001056456,0.0001842109,0.0001126729,0.0001200355,0.0001507253,0.0002163243,0.0004211939,0.0004745773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000249282,"about_ca_system_score_gemma":0.0002003933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009346099,"about_ca_topic_score_gemma":0.001844272,"domain_scores_codex":[0.9999481,0.00000411136,0.000004695222,0.00001601689,0.00001543346,0.00001174666],"domain_scores_gemma":[0.9999173,0.00001233616,0.00002290207,0.000007525126,0.00001027167,0.00002977091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002479058,0.000007410603,0.0004933865,0.00001732765,0.000002092696,0.00005988378,0.00000896188,0.00002931017,0.9984891,0.00005337629,0.00002527061,0.0007889393],"study_design_scores_gemma":[0.00005601369,0.0003773455,0.1109269,0.000021805,0.00004564124,0.003539519,0.0001138468,0.001724431,0.8625249,0.0001542078,0.02049926,0.00001612722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940069,0.0009002676,0.002032504,0.0001322769,0.00001871752,0.00003137634,0.001629132,0.00003371909,0.001215118],"genre_scores_gemma":[0.9740577,0.001027158,0.005164239,0.0001738453,0.00002343088,0.00005827878,0.01269733,0.00005209072,0.006745889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009346099,"threshold_uncertainty_score":0.002772212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009292628025787038,"score_gpt":0.1981367419846506,"score_spread":0.1888441139588635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}