{"id":"W4210368995","doi":"10.1021/acschemneuro.1c00621","title":"Insights into the Impact of Gold Nanoclusters Au<sub>10</sub>SG<sub>10</sub> on Human Microglia","year":2022,"lang":"en","type":"article","venue":"ACS Chemical Neuroscience","topic":"Nanocluster Synthesis and Applications","field":"Materials Science","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"European Regional Development Fund; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Nanoclusters; Microglia; Biomolecule; Chemistry; Cytosol; Biophysics; Lipid peroxidation; Acetylation; Neurodegeneration; Oxidative stress; Nanotechnology; Biochemistry; Biology; Materials science; Inflammation; Medicine; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001125157,0.000237645,0.0002361311,0.0001240626,0.0001313046,0.0001993659,0.0001390205,0.0003414267,0.0007459444],"category_scores_gemma":[0.0001230985,0.0001199656,0.0001636504,0.00006860267,0.0002576343,0.0001374896,0.0001574083,0.0002193473,0.0002065536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003615563,"about_ca_system_score_gemma":0.0002056791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001628936,"about_ca_topic_score_gemma":0.00240956,"domain_scores_codex":[0.9999102,0.00001501182,0.000005447125,0.00001903726,0.00002951216,0.00002067986],"domain_scores_gemma":[0.9999511,0.00001580873,0.000008829606,0.000004840409,0.00001104443,0.000008371328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000772077,0.00001004681,0.0001527203,0.00004490397,0.000004877094,0.00004486351,0.00001841996,0.0002310536,0.998302,0.00004725413,0.00002393663,0.001042678],"study_design_scores_gemma":[0.000008863522,0.0002549807,0.001728275,0.00000479614,0.00001561033,0.00008926054,0.0000591235,0.001635641,0.9954278,0.00006929028,0.0007026501,0.000003588048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949605,0.001736933,0.001883719,0.0001249086,0.00001713601,0.00001695657,0.00009203722,0.00005242342,0.001115423],"genre_scores_gemma":[0.9962082,0.0006342954,0.002311688,0.0001118188,0.000004401251,0.00001325742,0.00006238374,0.00001042679,0.0006435043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001628936,"threshold_uncertainty_score":0.003238916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02302920119394235,"score_gpt":0.2760130406348039,"score_spread":0.2529838394408616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}