{"id":"W4210371527","doi":"10.1139/cjc-2021-0281","title":"Anti-excitotoxicity and neuroprotective action of asiaticoside encapsulated polymeric nanoparticles in pilocarpine rodent seizure model","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Medicinal Plants and Neuroprotection","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Zeta potential; Neuroprotection; Chitosan; Membrane permeability; Pharmacology; Biophysics; Nuclear chemistry; Nanoparticle; Biochemistry; Membrane; Nanotechnology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005665218,0.0002591815,0.0001784307,0.000198849,0.0000878684,0.0001125127,0.0001246629,0.0001928636,0.0003908731],"category_scores_gemma":[0.00006461882,0.00006735083,0.0001627698,0.0001140271,0.0001286965,0.0001589753,0.0001044595,0.0002579609,0.0000693118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000153541,"about_ca_system_score_gemma":0.0001469578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001142392,"about_ca_topic_score_gemma":0.001719032,"domain_scores_codex":[0.9999639,0.000004104412,0.000003854466,0.000006386071,0.0000127436,0.000009098371],"domain_scores_gemma":[0.9999664,0.000003881536,0.00001215063,0.000003249204,0.000006904032,0.000007426509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008354555,0.00002323805,0.00004339373,0.00005108781,0.0000042605,0.00005426261,0.00001284019,0.00006633206,0.9975665,0.00003852043,0.0000357965,0.002020178],"study_design_scores_gemma":[0.0000096776,0.0004487624,0.001237241,0.000004823879,0.00002528728,0.0001310084,0.00001185288,0.0004983852,0.9968348,0.00002305993,0.0007713387,0.000003864377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941959,0.001609276,0.002286519,0.00007950615,0.00002144517,0.00002993224,0.0001145398,0.00009162279,0.001571239],"genre_scores_gemma":[0.9951745,0.001290407,0.002148872,0.00003480641,0.000006356666,0.00003198185,0.0001075784,0.00001102639,0.001194541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001142392,"threshold_uncertainty_score":0.002271473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01975630882887069,"score_gpt":0.2343824845716089,"score_spread":0.2146261757427382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}