{"id":"W4210433266","doi":"10.3389/fphys.2021.812882","title":"Human Beta Defensin 2 Ameliorated Alcohol-Associated Liver Disease in Mice","year":2022,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Biochemical effects in animals","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Lundbeckfonden; H. Lundbeck A/S; Novo Nordisk Fonden; National Institute of General Medical Sciences; Novo Nordisk; National Institute of Environmental Health Sciences; U.S. Department of Veterans Affairs","keywords":"Defensin; Liver disease; Alcohol; BETA (programming language); Medicine; Disease; Human disease; Pharmacology; Internal medicine; Chemistry; Biochemistry; Peptide; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002658909,0.0001888192,0.0005514834,0.000278746,0.00008087652,0.000004096642,0.0002030976,0.0001370304,0.0002226443],"category_scores_gemma":[0.000215652,0.000199838,0.00009899489,0.0006988979,0.000202686,0.00003346177,0.0002291415,0.0007082656,0.00001501458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004797894,"about_ca_system_score_gemma":0.00008674165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002303498,"about_ca_topic_score_gemma":0.00001886831,"domain_scores_codex":[0.9981165,0.0004412458,0.0003238092,0.000483317,0.0001856365,0.0004495214],"domain_scores_gemma":[0.9993795,0.00005776807,0.000108711,0.0002778879,0.0000381782,0.0001379578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001695491,0.001514081,0.1336159,0.0001203988,0.0001407079,0.0005751945,0.0003471274,0.0003046908,0.7458915,0.0001757854,0.1150235,0.0005955956],"study_design_scores_gemma":[0.004516736,0.0005699525,0.9823138,0.00008738248,0.00009628561,0.00000540575,0.000166979,0.003491563,0.00452384,0.002120455,0.001737047,0.000370568],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971019,0.001138865,0.000006501537,0.0003828989,0.0004576788,0.0004691015,0.00003640579,0.00006428343,0.0003423597],"genre_scores_gemma":[0.9970334,0.00002352716,0.0004779428,0.00168338,0.00006111931,0.00009074993,0.0002797858,0.00003349716,0.0003166252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8486978,"threshold_uncertainty_score":0.8149155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01501162153259646,"score_gpt":0.267271484445197,"score_spread":0.2522598629126006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}