{"id":"W4210448776","doi":"10.3390/cells11030440","title":"A Distinct Hibiscus sabdariffa Extract Prevents Iron Neurotoxicity, a Driver of Multiple Sclerosis Pathology","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Pharmacological Effects of Natural Compounds","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Hibiscus sabdariffa; Neurotoxicity; Neuroprotection; Pharmacology; Toxicity; Ferrous; Chemistry; Medicine; Biochemistry; Traditional medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009856204,0.0003498223,0.0005267348,0.0001589853,0.0005213043,0.00001404437,0.0008758116,0.0002752736,0.005562976],"category_scores_gemma":[0.0001566082,0.0003281781,0.0002867769,0.0003879017,0.0003849455,0.0001210029,0.001004714,0.001999493,0.0001048909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001794346,"about_ca_system_score_gemma":0.00007056975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001675025,"about_ca_topic_score_gemma":0.000006447684,"domain_scores_codex":[0.9956474,0.002157519,0.0005414964,0.0006031709,0.0003693241,0.0006811465],"domain_scores_gemma":[0.9974256,0.001524394,0.0003762695,0.0003306908,0.00006142126,0.0002816272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009536128,0.001662289,0.008620309,0.00007917533,0.00007488902,0.0002846232,0.0001875213,0.0009067698,0.9698594,0.00004372511,0.01058625,0.006741502],"study_design_scores_gemma":[0.008310981,0.002333645,0.0635822,0.00002192764,0.0004478112,0.0001416079,0.00007873766,0.005659648,0.833136,0.0008127521,0.08454543,0.0009292963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931782,0.000447068,0.00003890126,0.000308397,0.00226611,0.001197996,0.0003345016,0.0001394512,0.002089302],"genre_scores_gemma":[0.9965343,0.00005768397,0.0002411144,0.001817109,0.0001353406,0.000261979,0.0000464717,0.00004014406,0.0008658016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1367234,"threshold_uncertainty_score":0.999917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1188886657066084,"score_gpt":0.3786109996498136,"score_spread":0.2597223339432052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}