{"id":"W4210453930","doi":"10.1097/mph.0000000000002408","title":"Efficacy and Safety of Olanzapine in Children Receiving Highly Emetogenic Chemotherapy: A Randomized, Double-blind Placebo-controlled Phase 3 Trial","year":2022,"lang":"en","type":"article","venue":"Journal of Pediatric Hematology/Oncology","topic":"Nausea and vomiting management","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Olanzapine; Vomiting; Dopamine antagonist; Atypical antipsychotic; Schizophrenia (object-oriented programming); Nausea","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002209163,0.001273708,0.002839121,0.0004107596,0.0006258821,0.0009230923,0.0008802392,0.001574039,0.005801608],"category_scores_gemma":[0.002697279,0.0005233405,0.001977785,0.00042856,0.001101956,0.0009119978,0.0003326062,0.002085736,0.0006460506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001074918,"about_ca_system_score_gemma":0.002124655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009445259,"about_ca_topic_score_gemma":0.002543638,"domain_scores_codex":[0.9990783,0.0004788994,0.0001005277,0.0001321988,0.00009784936,0.0001121596],"domain_scores_gemma":[0.998331,0.0004305373,0.0006171923,0.00009964417,0.0001189407,0.0004027888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9771715,0.005278487,0.0007121857,0.0009865297,0.0006130695,0.00006714367,0.00005655666,0.0001444845,0.002096857,0.00008164945,0.0005773793,0.01221408],"study_design_scores_gemma":[0.9604454,0.0376436,0.0009165449,0.00004063121,0.000183437,0.00004022569,0.00001384035,0.0001452892,0.0002368905,0.00004769671,0.0002778987,0.000008565573],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806168,0.005388844,0.0009556264,0.0007491365,0.0004742203,0.009179357,0.001298668,0.0001575822,0.001179734],"genre_scores_gemma":[0.9751521,0.004048364,0.003421741,0.0010712,0.0004432467,0.0135903,0.0008112394,0.00003228945,0.001429363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005801608,"threshold_uncertainty_score":0.01940835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02521285971447234,"score_gpt":0.3421712278134867,"score_spread":0.3169583680990143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}