{"id":"W4210457640","doi":"10.3410/f.726769345.793573368","title":"Faculty Opinions recommendation of Into the clinic: Talimogene laherparepvec (T-VEC), a first-in-class intratumoral oncolytic viral therapy.","year":2020,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Oncolytic virus; Medicine; Viral therapy; Biosafety; Virotherapy; Limiting; Oncology; Melanoma; Immunotherapy; Cancer immunotherapy; Internal medicine; Cancer; Cancer research; Coronavirus disease 2019 (COVID-19); Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001153701,0.0008079177,0.001215987,0.003594072,0.0006072445,0.002804041,0.001938036,0.001320012,0.2319319],"category_scores_gemma":[0.01170221,0.0003678981,0.001216016,0.007050143,0.0002230852,0.001914236,0.001635498,0.001505624,0.1483756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001390036,"about_ca_system_score_gemma":0.004207663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.016841,"about_ca_topic_score_gemma":0.03782195,"domain_scores_codex":[0.9986467,0.0002242562,0.0002082579,0.0003447419,0.0004102933,0.0001658407],"domain_scores_gemma":[0.9942953,0.001398702,0.001024198,0.0006649886,0.001717051,0.0008997887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001124625,0.0000108037,0.001938691,0.001552504,0.00005638761,0.00002029611,0.00001418513,0.00007302508,0.0001004074,0.000366163,0.9878015,0.00795359],"study_design_scores_gemma":[0.0001895983,0.00001690092,0.004642626,0.000631372,0.00006319652,0.00004803837,0.00004162826,0.0001180207,0.0002368102,0.0005408599,0.9934561,0.00001479485],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0001318199,0.0002122394,0.00004971868,0.0002891817,0.00003974533,0.00002202843,0.9963259,0.0001951638,0.002734183],"genre_scores_gemma":[0.00102512,0.0005012444,0.0003716258,0.0003233433,0.00003312548,0.0001088889,0.9940258,0.0001146939,0.003496102],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.2319319,"threshold_uncertainty_score":0.7758894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03803480648956734,"score_gpt":0.3796048906951379,"score_spread":0.3415700842055706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}