{"id":"W4210526487","doi":"10.1002/agm2.12197","title":"Aging clocks &amp; mortality timers, methylation, glycomic, telomeric and more. A window to measuring biological age","year":2022,"lang":"en","type":"review","venue":"Aging Medicine","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Longevity; Biological age; Telomere; Epigenetics; Window of opportunity; Physiology; Biology; Senescence; Gerontology; Psychology; Medicine; Cell biology; Evolutionary biology; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001327919,0.000454411,0.00107685,0.0002279245,0.0002075628,0.00002527314,0.0002945455,0.000239804,0.0001102622],"category_scores_gemma":[0.0005692056,0.0003640694,0.0001808505,0.0003107794,0.0001525798,0.000003450172,0.0003970028,0.0003671123,0.000007800634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006474962,"about_ca_system_score_gemma":0.00008877179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001413858,"about_ca_topic_score_gemma":0.00001842787,"domain_scores_codex":[0.9974231,0.0003658987,0.0006577971,0.0008487234,0.0003320805,0.0003724216],"domain_scores_gemma":[0.9986705,0.0001332059,0.0003092522,0.0006106356,0.00004994913,0.0002265237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001252575,0.00004320439,0.001188071,0.001795417,0.0004972586,0.00003775498,0.000460542,0.00004848656,0.01341337,0.00001783785,0.0004172226,0.9820683],"study_design_scores_gemma":[0.0002560694,0.000135439,0.0005511392,0.0007503976,0.0003571607,0.00001789108,0.00003823814,0.000002989239,0.00019778,0.00004826005,0.9972338,0.0004108527],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008909302,0.98744,0.001987001,0.0001609966,0.0003365055,0.0006246932,0.0000186026,0.00003451175,0.0004883521],"genre_scores_gemma":[0.002713257,0.9936492,0.000950526,0.0002543427,0.000749711,0.0001026562,0.00118041,0.00006296443,0.0003368919],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9968166,"threshold_uncertainty_score":0.9998811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1478965523418383,"score_gpt":0.3849605997088464,"score_spread":0.2370640473670081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}