{"id":"W4210566864","doi":"10.1038/s41388-022-02205-0","title":"SMARCA4 biology in alveolar rhabdomyosarcoma","year":2022,"lang":"en","type":"article","venue":"Oncogene","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"SMARCA4; Biology; Epigenetics; Rhabdomyosarcoma; Cancer research; Alveolar rhabdomyosarcoma; Chromatin remodeling; Pathology; Sarcoma; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001984984,0.00008510749,0.0001005985,0.00004095977,0.00008209638,0.000004405951,0.0001815668,0.0000528144,0.0002272181],"category_scores_gemma":[0.00001790128,0.00009118851,0.00006137043,0.0001021794,0.00002829326,7.618909e-7,0.0002114169,0.00009872556,0.000008560266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004076491,"about_ca_system_score_gemma":0.00008943998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008919248,"about_ca_topic_score_gemma":0.00005963542,"domain_scores_codex":[0.9992448,0.00008798082,0.0001438317,0.0002579073,0.00007210569,0.0001933934],"domain_scores_gemma":[0.9996608,0.000005858613,0.00003726609,0.000245241,0.00001502713,0.00003578992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005451135,0.00007265899,0.005453369,0.000004800566,0.00001707265,0.000007047136,0.00003757754,0.0008925761,0.9756572,0.0000979909,0.001833022,0.01587221],"study_design_scores_gemma":[0.001843325,0.000672623,0.001099263,0.000006376642,0.00001235922,0.00009578509,0.0001983376,0.001227285,0.2168353,0.000888004,0.7767054,0.0004159696],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932088,0.002823151,0.0003650138,0.0002053832,0.0002033046,0.00007970768,0.00003165847,0.00001077314,0.003072258],"genre_scores_gemma":[0.9976166,0.0001058753,0.0006635719,0.000534668,0.000141407,0.00005967226,0.0001666763,0.00001610075,0.000695385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7748724,"threshold_uncertainty_score":0.371856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00849272556272753,"score_gpt":0.2642316653957369,"score_spread":0.2557389398330094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}