{"id":"W4210584235","doi":"10.3410/f.718029891.793480368","title":"Faculty Opinions recommendation of Temporal regulation of EGF signalling networks by the scaffold protein Shc1.","year":2013,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Scaffold protein; GRB2; Signal transducing adaptor protein; Phosphorylation; Signal transduction; Protein tyrosine phosphatase; Cell biology; Biology; Interactome; Kinase; Receptor; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0022342,0.0006787016,0.000489679,0.001687336,0.001739361,0.003978289,0.001160687,0.003276198,0.4704621],"category_scores_gemma":[0.005868211,0.0004170308,0.0007495539,0.001788006,0.0005544474,0.001688651,0.001642951,0.002706874,0.2170248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003350522,"about_ca_system_score_gemma":0.008546581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01122042,"about_ca_topic_score_gemma":0.03424596,"domain_scores_codex":[0.9982216,0.00008648316,0.00007808246,0.0001630805,0.00122391,0.0002268669],"domain_scores_gemma":[0.9908499,0.0003112869,0.0003660385,0.0003608562,0.005122276,0.002989663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002716459,0.000028791,0.0001740293,0.0001338048,0.000004467232,0.00006034227,0.00002248331,0.00003816734,0.00108253,0.0009435856,0.9555529,0.04193178],"study_design_scores_gemma":[0.000007974813,0.00001251348,0.0004694891,0.0000718629,0.000003949081,0.00002118712,0.00002931847,0.00004689128,0.00026485,0.0003824234,0.9986841,0.000005341572],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"dataset","genre_scores_codex":[0.001511775,0.006635593,0.003259403,0.141108,0.1462099,0.0005936963,0.01194458,0.001743776,0.6869933],"genre_scores_gemma":[0.004757657,0.006677943,0.001775512,0.01346344,0.02447695,0.0001163442,0.003972765,0.0003889966,0.9443703],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.4704621,"threshold_uncertainty_score":0.7553215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02147610393843338,"score_gpt":0.3208060057001273,"score_spread":0.2993299017616939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}