{"id":"W4210599191","doi":"10.21203/rs.3.rs-1259439/v1","title":"Unique metabolic profiles of Blautia wexlerae achieve beneficial effects for the control of obesity and type 2 diabetes","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"ASTER","funders":"National Institutes of Biomedical Innovation, Health and Nutrition; Institute of Medical Science, University of Tokyo; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Ono Medical Research Foundation; University of Tokyo; Japan Agency for Medical Research and Development; Canon Foundation in Europe","keywords":"Gut flora; Metabolism; Obesity; Carbohydrate metabolism; Diabetes mellitus; Biology; Type 2 diabetes; Metabolic pathway; Biochemistry; Endocrinology; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001453505,0.0005837999,0.0003997619,0.0004697149,0.0003032205,0.0004124073,0.000147917,0.0003464559,0.001305206],"category_scores_gemma":[0.0001226135,0.000153395,0.0003126808,0.0003339757,0.0002052205,0.0003550877,0.0003998086,0.0007263864,0.00026252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001297183,"about_ca_system_score_gemma":0.0002084309,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009242006,"about_ca_topic_score_gemma":0.001230169,"domain_scores_codex":[0.9998912,0.00001458545,0.000008767984,0.00002987343,0.00002309122,0.0000324208],"domain_scores_gemma":[0.9999037,0.000006487199,0.00003300988,0.000007466357,0.00001492092,0.00003442998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000229433,0.00005754937,0.0007978681,0.00004608738,0.00001061528,0.00003345336,0.00002919708,0.00001747442,0.9963319,0.00003750431,0.00003819131,0.00237077],"study_design_scores_gemma":[0.00008076192,0.002511368,0.1833674,0.00009892619,0.0001811845,0.0006844289,0.0004863867,0.0004347805,0.7960506,0.0002910327,0.01576951,0.00004361497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940901,0.002411192,0.001325583,0.0002385655,0.00006465497,0.00003450683,0.0005970347,0.00004845695,0.001189774],"genre_scores_gemma":[0.9836193,0.0019957,0.00584665,0.0003322419,0.00004348421,0.00005631807,0.001327617,0.00004761336,0.006731108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001305206,"threshold_uncertainty_score":0.004366279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02124904859890516,"score_gpt":0.3505933797053244,"score_spread":0.3293443311064193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}