{"id":"W4210630588","doi":"10.1002/alz.056446","title":"Differential cognitive correlates of tau and neurofilament light chain in cerebrospinal fluid of frontotemporal lobar degeneration patients with and without Alzheimer’s markers","year":2021,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor; Western University; Occupational Cancer Research Centre; Toronto Western Hospital; University of Toronto; University Health Network","funders":"","keywords":"Frontotemporal lobar degeneration; Progressive supranuclear palsy; Primary progressive aphasia; Corticobasal degeneration; Pathology; Frontotemporal dementia; Psychology; Medicine; Cerebrospinal fluid; Tau protein; Neuropsychology; Internal medicine; Alzheimer's disease; Audiology; Atrophy; Neuroscience; Cognition; Disease; Dementia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003041771,0.0005698747,0.0004895348,0.001497275,0.0007547113,0.0007347199,0.0002702219,0.0005440286,0.001316758],"category_scores_gemma":[0.001975941,0.0002519873,0.0002505291,0.0006810533,0.0005276383,0.0004487562,0.0004107881,0.0003346233,0.0003319751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004792335,"about_ca_system_score_gemma":0.0002807458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004960428,"about_ca_topic_score_gemma":0.003643068,"domain_scores_codex":[0.9997166,0.00003597592,0.00004556852,0.00007079936,0.00005844099,0.00007276248],"domain_scores_gemma":[0.9994327,0.0001194238,0.0001641443,0.00002873072,0.0001018842,0.0001530043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001173223,0.0001475802,0.9905571,0.00002041644,0.00006143121,0.001762182,0.0005691226,0.00004079673,0.003391645,0.0000232705,0.0001073238,0.002145834],"study_design_scores_gemma":[0.00002286634,0.0002306148,0.9972173,0.000006470252,0.00002209803,0.001546735,0.0004185674,0.00007873672,0.0003038744,0.00004082342,0.0001064843,0.000005435586],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997204,0.00006389721,0.00001019153,0.000007611315,0.000002663026,0.000001956303,0.00006540774,0.000001043499,0.0001269655],"genre_scores_gemma":[0.9996718,0.00003194713,0.00002349446,0.000014462,0.000006448573,0.000003500745,0.0001694559,8.188336e-7,0.00007804243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004960428,"threshold_uncertainty_score":0.009863079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01514510701817204,"score_gpt":0.264796751016575,"score_spread":0.2496516439984029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}