{"id":"W4210641702","doi":"10.3389/fnagi.2021.772136","title":"Intrinsic Brain Activity of Inferior Temporal Region Increased in Prodromal Alzheimer's Disease With Hearing Loss","year":2022,"lang":"en","type":"article","venue":"Frontiers in Aging Neuroscience","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Janssen Alzheimer Immunotherapy Research And Development; Canadian Institutes of Health Research; National Institute of Biomedical Imaging and Bioengineering; National Key Research and Development Program of China; University of California, San Diego; Fundamental Research Funds for the Central Universities; National Institutes of Health; H. Lundbeck A/S; Servier; National Natural Science Foundation of China; Eisai; Genentech; IXICO; Biogen; Pfizer; Novartis Pharmaceuticals Corporation; Northern California Institute for Research and Education; F. Hoffmann-La Roche; University of Southern California; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association","keywords":"Audiology; Neuropsychology; Cognition; Resting state fMRI; Voxel; Medicine; Psychology; Cognitive decline; Voxel-based morphometry; Bonferroni correction; Hearing loss; Neuroscience; Internal medicine; Disease; Dementia; Magnetic resonance imaging; Radiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002806826,0.0002265832,0.0001873944,0.0004204166,0.0001626757,0.0002707129,0.0001302101,0.0001574598,0.001400947],"category_scores_gemma":[0.0007967683,0.00008064285,0.0001814548,0.0002911648,0.0001976747,0.0001656874,0.0002056524,0.0001320276,0.0000862282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001949516,"about_ca_system_score_gemma":0.0001300209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003043163,"about_ca_topic_score_gemma":0.005464004,"domain_scores_codex":[0.9999243,0.00001233513,0.000008526396,0.0000238285,0.00001343964,0.00001741842],"domain_scores_gemma":[0.9997777,0.00006055156,0.00008727502,0.00001937618,0.00002109962,0.00003399824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003527219,0.0001309853,0.9318434,0.0000956919,0.000157165,0.002039242,0.0004914533,0.000317245,0.04699646,0.000114199,0.0002986642,0.01398828],"study_design_scores_gemma":[0.000008076233,0.0001155292,0.9984073,0.000002028732,0.00002589084,0.0005807044,0.00005240144,0.0002177644,0.0004651195,0.00006021782,0.00006345256,0.000001627347],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992115,0.000158269,0.0001457709,0.00001170668,0.000001970488,0.000006234717,0.0001456211,0.000004142137,0.0003147352],"genre_scores_gemma":[0.9995731,0.00003758349,0.0001101753,0.000008199338,0.000005081155,0.000005290509,0.0001261072,0.000001387893,0.000133058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003043163,"threshold_uncertainty_score":0.006050944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03705793390477582,"score_gpt":0.2684687736187141,"score_spread":0.2314108397139382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}