{"id":"W4210647050","doi":"10.1016/j.gene.2022.146211","title":"Meta-analysis of microRNA profiling data does not reveal a consensus signature for B cell acute lymphoblastic leukemia","year":2022,"lang":"en","type":"review","venue":"Gene","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"microRNA; Biology; Computational biology; Gene expression profiling; Meta-analysis; Bioinformatics; Genetics; Gene; Gene expression; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002538267,0.0008520343,0.003760087,0.001594068,0.0001348147,0.00169317,0.001017752,0.000694022,0.001146405],"category_scores_gemma":[0.003216434,0.0003147397,0.001399148,0.002577821,0.0004203375,0.0008401253,0.0006578073,0.001319165,0.000526089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006062401,"about_ca_system_score_gemma":0.001269354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007390428,"about_ca_topic_score_gemma":0.001855234,"domain_scores_codex":[0.9992836,0.0001680057,0.00009543307,0.00025512,0.000160988,0.00003690898],"domain_scores_gemma":[0.9979419,0.001444667,0.0002583369,0.00007498819,0.0002248935,0.00005513975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0005082171,0.00002785452,0.005810136,0.01986605,0.004942036,0.0002605615,0.0000515318,0.0006319166,0.004408177,0.0017286,0.01014048,0.9516245],"study_design_scores_gemma":[0.0003681241,0.0007267534,0.05668055,0.01976817,0.03352346,0.006567528,0.0003111995,0.002041415,0.008571436,0.01467015,0.8565394,0.0002317224],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009528576,0.9973168,0.0006831495,0.0003756113,0.0001322575,0.000005303549,0.0001927134,0.00001733675,0.000323998],"genre_scores_gemma":[0.0130503,0.9822244,0.002300456,0.001100186,0.0003739948,0.00002298439,0.0006165692,0.00002671084,0.000284427],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003760087,"threshold_uncertainty_score":0.0134238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0905908047714059,"score_gpt":0.3299058789038747,"score_spread":0.2393150741324688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}