{"id":"W4210650909","doi":"10.1097/01.hs9.0000821448.70992.5a","title":"S120: RANDOMIZED CONTROLLED TRIAL OF THE EFFICACY AND SAFETY OF DEFERIPRONE: SUBGROUP ANALYSIS OF PEDIATRIC PATIENTS IN IRON-OVERLOADED PATIENTS WITH SICKLE CELL DISEASE AND OTHER ANEMIAS","year":2022,"lang":"en","type":"article","venue":"HemaSphere","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Deferiprone; Medicine; Deferoxamine; Clinical endpoint; Population; Anemia; Deferasirox; Sickle cell anemia; Thalassemia; Adverse effect; Randomized controlled trial; Subgroup analysis; Pediatrics; Internal medicine; Clinical trial; Disease; Meta-analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000330618,0.0001619862,0.001366014,0.0001183962,0.00005456619,0.000002615263,0.00007003906,0.00006255344,0.0002602797],"category_scores_gemma":[0.0002163077,0.00009217134,0.0002556413,0.0007487457,0.000164242,0.00002267551,0.00007753104,0.0001607237,1.447095e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002817915,"about_ca_system_score_gemma":0.00009071922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001342189,"about_ca_topic_score_gemma":0.00001610627,"domain_scores_codex":[0.9981388,0.0003211178,0.0007131443,0.0002195739,0.0004570408,0.0001503515],"domain_scores_gemma":[0.9987195,0.0003317885,0.0005269005,0.0002574766,0.00007581204,0.0000884913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6316195,0.001529004,0.365176,0.0001734237,0.0003951125,0.000001025782,0.0005643332,0.0003933624,0.00001651056,0.00001166863,0.00002419592,0.00009594193],"study_design_scores_gemma":[0.8325365,0.0005536107,0.1611947,0.00002883496,0.004928322,8.097245e-8,0.0003043352,0.0003308602,0.00001549846,0.000005577662,0.00001158281,0.00009004473],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942456,0.001282033,0.000002906511,0.00003374401,0.00005012706,0.003823226,0.00007914536,0.000005118078,0.0004780406],"genre_scores_gemma":[0.9995445,0.0001559868,0.00002294446,0.000048248,0.000008842729,0.00007657366,0.00002993926,0.00001696493,0.000096008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2039813,"threshold_uncertainty_score":0.3758639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003304192403148001,"score_gpt":0.1953022631052273,"score_spread":0.1919980707020793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}