{"id":"W4210650909","doi":"10.1097/01.hs9.0000821448.70992.5a","title":"S120: RANDOMIZED CONTROLLED TRIAL OF THE EFFICACY AND SAFETY OF DEFERIPRONE: SUBGROUP ANALYSIS OF PEDIATRIC PATIENTS IN IRON-OVERLOADED PATIENTS WITH SICKLE CELL DISEASE AND OTHER ANEMIAS","year":2022,"lang":"en","type":"article","venue":"HemaSphere","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Deferiprone; Medicine; Deferoxamine; Clinical endpoint; Population; Anemia; Deferasirox; Sickle cell anemia; Thalassemia; Adverse effect; Randomized controlled trial; Subgroup analysis; Pediatrics; Internal medicine; Clinical trial; Disease; Meta-analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001696709,0.00171692,0.004038781,0.0004248129,0.000288533,0.0008952005,0.0007400312,0.001579199,0.006037684],"category_scores_gemma":[0.002788844,0.0004849759,0.003440451,0.0004242947,0.000493958,0.000638577,0.0003944679,0.001913737,0.0003904903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008196856,"about_ca_system_score_gemma":0.001179132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001096574,"about_ca_topic_score_gemma":0.002558291,"domain_scores_codex":[0.9990007,0.0005687518,0.00009796202,0.0001625547,0.00006662481,0.0001034421],"domain_scores_gemma":[0.9988781,0.0003605395,0.000396418,0.00007413924,0.00007874137,0.0002121954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9849712,0.0008985154,0.001198351,0.001091819,0.004354816,0.00004846327,0.0000326911,0.0001569649,0.0008254497,0.0000745326,0.0005344144,0.005812798],"study_design_scores_gemma":[0.9618058,0.02935902,0.003665353,0.0001054613,0.003615605,0.00005236846,0.00003550948,0.0004182499,0.0001834932,0.0001672015,0.0005738161,0.00001819381],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724998,0.01566169,0.0006490138,0.001060469,0.0006596978,0.005086532,0.002531194,0.0001175064,0.001734196],"genre_scores_gemma":[0.9858181,0.003446238,0.001095757,0.001075291,0.0004752959,0.005208428,0.001604527,0.00001469386,0.001261771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006037684,"threshold_uncertainty_score":0.02019805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003304192403148001,"score_gpt":0.1953022631052273,"score_spread":0.1919980707020793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}